[HTML][HTML] Stapled peptides inhibitors: a new window for target drug discovery
AM Ali, J Atmaj, N Van Oosterwijk, MR Groves… - Computational and …, 2019 - Elsevier
Protein-protein interaction (PPI) is a hot topic in clinical research as protein networking has a
major impact in human disease. Such PPIs are potential drugs targets, leading to the need …
major impact in human disease. Such PPIs are potential drugs targets, leading to the need …
The different facets of organelle interplay—an overview of organelle interactions
Membrane-bound organelles such as mitochondria, peroxisomes, or the endoplasmic
reticulum (ER) create distinct environments to promote specific cellular tasks such as ATP …
reticulum (ER) create distinct environments to promote specific cellular tasks such as ATP …
Newly born peroxisomes are a hybrid of mitochondrial and ER-derived pre-peroxisomes
A Sugiura, S Mattie, J Prudent, HM McBride - Nature, 2017 - nature.com
Peroxisomes function together with mitochondria in a number of essential biochemical
pathways, from bile acid synthesis to fatty acid oxidation. Peroxisomes grow and divide from …
pathways, from bile acid synthesis to fatty acid oxidation. Peroxisomes grow and divide from …
SIRT 5 inhibits peroxisomal ACOX 1 to prevent oxidative damage and is downregulated in liver cancer
Peroxisomes account for~ 35% of total H2O2 generation in mammalian tissues. Peroxisomal
ACOX 1 (acyl‐CoA oxidase 1) is the first and rate‐limiting enzyme in fatty acid β‐oxidation …
ACOX 1 (acyl‐CoA oxidase 1) is the first and rate‐limiting enzyme in fatty acid β‐oxidation …
Towards repurposing the yeast peroxisome for compartmentalizing heterologous metabolic pathways
Compartmentalization of enzymes into organelles is a promising strategy for limiting
metabolic crosstalk and improving pathway efficiency, but improved tools and design rules …
metabolic crosstalk and improving pathway efficiency, but improved tools and design rules …
Spatiotemporal contact between peroxisomes and lipid droplets regulates fasting-induced lipolysis via PEX5
Lipid droplets (LDs) are key subcellular organelles for regulating lipid metabolism. Although
several subcellular organelles participate in lipid metabolism, it remains elusive whether …
several subcellular organelles participate in lipid metabolism, it remains elusive whether …
Molecular nanoinformatics approach assessing the biocompatibility of biogenic silver nanoparticles with channelized intrinsic steatosis and apoptosis
The developmental rapidity of nanotechnology poses higher risks of exposure to humans
and the environment through manufactured nanomaterials. The multitude of biological …
and the environment through manufactured nanomaterials. The multitude of biological …
[HTML][HTML] Crosstalk between mitochondria and peroxisomes
J Demarquoy, F Le Borgne - World journal of biological chemistry, 2015 - ncbi.nlm.nih.gov
Mitochondria and peroxisomes are small ubiquitous organelles. They both play major roles
in cell metabolism, especially in terms of fatty acid metabolism, reactive oxygen species …
in cell metabolism, especially in terms of fatty acid metabolism, reactive oxygen species …
Peroxisome biogenesis, membrane contact sites, and quality control
Peroxisomes are conserved organelles of eukaryotic cells with important roles in cellular
metabolism, human health, redox homeostasis, as well as intracellular metabolite transfer …
metabolism, human health, redox homeostasis, as well as intracellular metabolite transfer …
Dynamics of peroxisome homeostasis and its role in stress response and signaling in plants
Peroxisomes play vital roles in plant growth, development, and environmental stress
response. During plant development and in response to environmental stresses, the number …
response. During plant development and in response to environmental stresses, the number …