The concept of mismatch repair (MMR) was formulated independently in 1964 to explain the
removal of brominated nucleotides from DNA as well as gene conversion during genetic …

The mismatch repair (MMR) system detects non-Watson–Crick base pairs and strand
misalignments arising during DNA replication and mediates their removal by catalyzing …

Mutations are rare events, occurring spontaneously at a frequency of 1 per 109-1010 base
pairs per cell division. 1, 2 Nucleotide misincorporation during DNA synthesis yields …

Although homologous recombination and DNA repair phenomena in bacteria were initially
extensively studied without regard to any relationship between the two, it is now appreciated …

We describe an analysis of genome variation in 825 P. falciparum samples from Asia and
Africa that identifies an unusual pattern of parasite population structure at the epicenter of …

▪ Abstract Mismatch repair (MMR) systems play a central role in promoting genetic stability
by repairing DNA replication errors, inhibiting recombination between non-identical DNA …

ABSTRACT Phytoplasmas (“Candidatus Phytoplasma,” class Mollicutes) cause disease in
hundreds of economically important plants and are obligately transmitted by sap-feeding …

▪ Abstract DNA mismatch repair (MMR) guards the integrity of the genome in virtually all
cells. It contributes about 1000-fold to the overall fidelity of replication and targets mispaired …

The MutL DNA mismatch repair protein has recently been shown to be an ATPase and to
belong to an emerging ATPase superfamily that includes DNA topoisomerase II and Hsp90 …

MutL and its homologs are essential for DNA mismatch repair. Mutations in genes encoding
human homologs of MutL cause multiorgan cancer susceptibility. We have determined the …