Manmade electromagnetic fields and oxidative stress—biological effects and consequences for health

D Schuermann, M Mevissen - International journal of molecular sciences, 2021 - mdpi.com
Concomitant with the ever-expanding use of electrical appliances and mobile
communication systems, public and occupational exposure to electromagnetic fields (EMF) …

Oxidative mechanisms of biological activity of low-intensity radiofrequency radiation

I Yakymenko, O Tsybulin, E Sidorik… - … biology and medicine, 2016 - Taylor & Francis
This review aims to cover experimental data on oxidative effects of low-intensity
radiofrequency radiation (RFR) in living cells. Analysis of the currently available peer …

Resveratrol attenuates hypoxia-induced neuronal cell death, inflammation and mitochondrial oxidative stress by modulation of TRPM2 channel

Y Akyuva, M Nazıroğlu - Scientific Reports, 2020 - nature.com
Hypoxia (HYPX) induced-overload Ca2+ entry results in increase of mitochondrial oxidative
stress, inflammation and apoptosis in several neurons. Ca2+ permeable TRPM2 channel …

Pharmacological approaches to improving cognitive function in Down syndrome: current status and considerations

KJ Gardiner - Drug design, development and therapy, 2014 - Taylor & Francis
Down syndrome (DS), also known as trisomy 21, is the most common genetic cause of
intellectual disability (ID). Although ID can be mild, the average intelligence quotient is in the …

Synergic effects of doxorubicin and melatonin on apoptosis and mitochondrial oxidative stress in MCF-7 breast cancer cells: involvement of TRPV1 channels

PA Koşar, M Nazıroğlu, İS Övey, B Çiğ - The Journal of membrane biology, 2016 - Springer
Transient receptor transient receptor potential vanilloid 1 (TRPV1) is a Ca 2+-permeable
channel gated by oxidative stress and capsaicin (CAP) and modulated by melatonin (MEL) …

Effects of 3.5 GHz radiofrequency radiation on ghrelin, nesfatin-1, and irisin level in diabetic and healthy brains

H Bektas, S Algul, F Altindag, K Yegin… - Journal of chemical …, 2022 - Elsevier
Diabetes, mobile phone use, and obesity have increased simultaneously in recent years.
The radiofrequency radiation (RFR) emitted from mobile phones is largely absorbed in the …

Oxidative stress-modulated TRPM ion channels in cell dysfunction and pathological conditions in humans

F Simon, D Varela, C Cabello-Verrugio - Cellular signalling, 2013 - Elsevier
The transient receptor potential melastatin (TRPM) protein family is an extensive group of
ion channels expressed in several types of mammalian cells. Many studies have shown that …

Protective effects of melatonin against oxidative injury in rat testis induced by wireless (2.45 GHz) devices

T Oksay, M Naziroğlu, S Doğan, A Güzel… - Andrologia, 2014 - Wiley Online Library
Wireless devices have become part of everyday life and mostly located near reproductive
organs while they are in use. The present study was designed to determine the possible …

Radiation inhibits salivary gland function by promoting STIM1 cleavage by caspase-3 and loss of SOCE through a TRPM2-dependent pathway

X Liu, B Gong, LB de Souza, HL Ong, KP Subedi… - Science …, 2017 - science.org
Store-operated Ca2+ entry (SOCE) is critical for salivary gland fluid secretion. We report that
radiation treatment caused persistent salivary gland dysfunction by activating a TRPM2 …

Diabetes enhances oxidative stress-induced TRPM2 channel activity and its control by N-acetylcysteine in rat dorsal root ganglion and brain

E Sözbir, M Nazıroğlu - Metabolic brain disease, 2016 - Springer
N-acetylcysteine (NAC) is a sulfhydryl donor antioxidant that contributes to the regeneration
of glutathione (GSH) and also scavengers via a direct reaction with free oxygen radicals …