HIV and antiretroviral therapy-related fat alterations

JR Koethe, C Lagathu, JE Lake, P Domingo… - Nature reviews Disease …, 2020 - nature.com
Early in the HIV epidemic, lipodystrophy, characterized by subcutaneous fat loss
(lipoatrophy), with or without central fat accumulation (lipohypertrophy), was recognized as a …

A review of the toxicity of HIV medications

AM Margolis, H Heverling, PA Pham… - Journal of Medical …, 2014 - Springer
Antiretroviral therapy has changed human immunodeficiency virus (HIV) infection from a
near-certainly fatal illness to one that can be managed chronically. More patients are taking …

Obesity and weight gain in persons with HIV

SS Bailin, CL Gabriel, CN Wanjalla… - Current HIV/AIDS Reports, 2020 - Springer
Abstract Purpose of Review The proportion of overweight and obese persons with HIV
(PWH) has increased since the introduction of antiretroviral therapy (ART). We aim to …

[图书][B] HIV and the pathogenesis of AIDS.

JA Levy - 1994 - cabidigitallibrary.org
This book grew out of a scientific review, originally published in Microbiological Reviews. It
has been updated and expanded-now citing more than 2100 references (100 pages of the …

[HTML][HTML] Workshop on HIV infection and aging: what is known and future research directions

RB Effros, CV Fletcher, K Gebo, JB Halter… - … diseases: an official …, 2008 - ncbi.nlm.nih.gov
Highly active antiretroviral treatment has resulted in dramatically increased life expectancy
among patients with HIV infection who are now aging while receiving treatment and are at …

[HTML][HTML] Leptin at 14 y of age: an ongoing story

JM Friedman - The American journal of clinical nutrition, 2009 - Elsevier
The cloning of the ob gene and its gene product leptin has led to the elucidation of a robust
physiologic system that maintains constancy of fat stores. Leptin is a peptide hormone …

Cohort profile: the centers for AIDS research network of integrated clinical systems

MM Kitahata, B Rodriguez, R Haubrich… - International journal …, 2008 - academic.oup.com
Highly active antiretroviral therapy (HAART) delays disease progression and death. 1–4
However, the treatments incompletely control HIV replication, 5–7 only partially restore …

Metabolic outcomes in a randomized trial of nucleoside, nonnucleoside and protease inhibitor-sparing regimens for initial HIV treatment

RH Haubrich, SA Riddler, AG DiRienzo, L Komarow… - Aids, 2009 - journals.lww.com
Background: The metabolic effects of initial therapy for HIV-1 infection are important
determinants of regimen selection. Methods: Open-label study in 753 subjects randomized …

Low CD4+ T-cell count as a major atherosclerosis risk factor in HIV-infected women and men

RC Kaplan, LA Kingsley, SJ Gange, L Benning… - Aids, 2008 - journals.lww.com
Objective: To assess the association of HIV infection, HIV disease parameters (including
CD4+ T-cell counts, HIV viral load, and AIDS) and antiretroviral medication use with …

Leptin and the regulation of body weigh

JM Friedman - The Keio journal of medicine, 2011 - jstage.jst.go.jp
The ob gene was cloned in 1994 using the methodology of positional cloning. Leptin, the
protein encoded by the ob gene, was identified in 1995 and shown to be a hormonal signal …