Therapeutic implications of caffeic acid in cancer and neurological diseases

M Alam, S Ahmed, AM Elasbali, M Adnan… - Frontiers in …, 2022 - frontiersin.org
Caffeic acid (CA) is found abundantly in fruits, vegetables, tea, coffee, oils, and more. CA
and its derivatives have been used for many centuries due to their natural healing and …

Biomedical features and therapeutic potential of rosmarinic acid

S Noor, T Mohammad, MA Rub, A Raza… - Archives of Pharmacal …, 2022 - Springer
For decades, the use of secondary metabolites of various herbs has been an attractive
strategy in combating human diseases. Rosmarinic acid (RA) is a bioactive phenolic …

[HTML][HTML] Recent advances in the therapeutic potential of emodin for human health

J Sharifi-Rad, J Herrera-Bravo, S Kamiloglu… - Biomedicine & …, 2022 - Elsevier
Abstract Emodin (1, 3, 8-trihydroxy-6-methylanthraquinone) is a bioactive compound, a
natural anthraquinone aglycone, present mainly in herbaceous species of the families …

Bax/Bcl-2 cascade is regulated by the EGFR pathway: therapeutic targeting of non-small cell lung cancer

M Alam, S Alam, A Shamsi, M Adnan… - Frontiers in …, 2022 - frontiersin.org
Non-small cell lung carcinoma (NSCLC) comprises 80%–85% of lung cancer cases. EGFR
is involved in several cancer developments, including NSCLC. The EGFR pathway …

Utilisation of Mangifera indica plant extracts and parts in antimicrobial formulations and as a pharmaceutical excipient: a review

MA Alaiya, MA Odeniyi - Future Journal of Pharmaceutical Sciences, 2023 - Springer
Background Antimicrobial resistance and the environmental threat posed by some synthetic
antimicrobial agents necessitate more research into development of novel pharmaceutical …

[HTML][HTML] Natural tannins as anti-SARS-CoV-2 compounds

SC Wang, IW Chou, MC Hung - International Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Tannins are polyphenols enriched in wood, bark, roots, leaves, seeds and fruits of a variety
of plants. Over the last two decades, there has been an increasing interest in understanding …

[HTML][HTML] Investigating regulated signaling pathways in therapeutic targeting of non-small cell lung carcinoma

M Alam, GM Hasan, SM Eldin, M Adnan… - Biomedicine & …, 2023 - Elsevier
Non-small cell lung carcinoma (NSCLC) is the most common malignancy worldwide. The
signaling cascades are stimulated via genetic modifications in upstream signaling …

p53/NF-kB balance in SARS-CoV-2 infection: From OMICs, genomics and pharmacogenomics insights to tailored therapeutic perspectives (COVIDomics)

D Milani, L Caruso, E Zauli, AM Al Owaifeer… - Frontiers in …, 2022 - frontiersin.org
SARS-CoV-2 infection affects different organs and tissues, including the upper and lower
airways, the lung, the gut, the olfactory system and the eye, which may represent one of the …

Therapeutic targeting of regulated signaling pathways of non-small cell lung carcinoma

GM Hasan, MI Hassan, SS Sohal, A Shamsi… - ACS omega, 2023 - ACS Publications
Non-small cell lung carcinoma (NSCLC) is the most common cancer globally.
Phytochemicals and small molecule inhibitors significantly prevent varying types of cancers …

Anti-COVID-19 Potential of Ellagic Acid and Polyphenols of Punica granatum L.

R Alexova, S Alexandrova, S Dragomanova, R Kalfin… - Molecules, 2023 - mdpi.com
Pomegranate (Punica granatum L.) is a rich source of polyphenols, including ellagitannins
and ellagic acid. The plant is used in traditional medicine, and its purified components can …