The molecular basis of resilience: a narrative review

M Ryan, R Ryznar - Frontiers in Psychiatry, 2022 - frontiersin.org
Resilience refers to the adaptability of a person–an ability to “bounce-back” from stressors.
We question if resilience can be strengthened, potentially to decrease the risk of stress …

Cancer‐related inflammation and depressive symptoms: Systematic review and meta‐analysis

DC McFarland, M Doherty, TM Atkinson, R O'Hanlon… - Cancer, 2022 - Wiley Online Library
Background Depressive symptoms in patients with cancer are associated with poor quality
of life and decreased survival. Although inflammation is reliably associated with depression …

The potential role of dysfunctions in neuron-microglia communication in the pathogenesis of brain disorders

K Chamera, E Trojan… - Current …, 2020 - ingentaconnect.com
The bidirectional communication between neurons and microglia is fundamental for the
proper functioning of the central nervous system (CNS). Chemokines and clusters of …

Depression and cardiovascular disease: the viewpoint of platelets

P Amadio, M Zarà, L Sandrini, A Ieraci… - International journal of …, 2020 - mdpi.com
Depression is a major cause of morbidity and low quality of life among patients with
cardiovascular disease (CVD), and it is now considered as an independent risk factor for …

Understanding the basis of major depressive disorder in oncological patients: Biological links, clinical management, challenges, and lifestyle medicine

O Fraile-Martinez, MA Alvarez-Mon… - Frontiers in …, 2022 - frontiersin.org
In recent years, the incidence of different types of cancer and patient survival have been
rising, as well as their prevalence. The increase in survival in recent years exposes the …

Metabolomic biomarkers in anxiety disorders

E Humer, C Pieh, T Probst - International Journal of Molecular Sciences, 2020 - mdpi.com
Anxiety disorders range among the most prevalent psychiatric disorders and belong to the
leading disorders in the study of the total global burden of disease. Anxiety disorders are …

Neuro-inflammaging and psychopathological distress

G Murdaca, F Paladin, M Casciaro, CM Vicario… - Biomedicines, 2022 - mdpi.com
Inflammaging is a low degree of chronic and systemic tissue inflammation associated with
aging, and is intimately linked to pro-inflammatory mediators. These substances are …

Melatonin reverses the depression-associated behaviour and regulates microglia, fractalkine expression and neurogenesis in adult mice exposed to chronic mild …

NM Vega-Rivera, L Ortiz-López, A Granados-Juárez… - Neuroscience, 2020 - Elsevier
Depression may be precipitated by the negative impact of chronic stress, which is
considered to play a key role in this neuropsychiatric disorder. Interestingly, depressed …

Inflammatory mediators and dual depression: Potential biomarkers in plasma of primary and substance-induced major depression in cocaine and alcohol use …

N García-Marchena, M Barrera, JI Mestre-Pintó… - PLoS …, 2019 - journals.plos.org
Major depressive disorder (MDD) is the most prevalent comorbid mental disorder among
people with substance use disorders. The MDD can be both primary and substance-induced …

[HTML][HTML] The complex role of the chemokine CX3CL1/Fractalkine in major depressive disorder: A narrative review of preclinical and clinical studies

S Bridge, SN Karagiannis, A Borsini - Brain, Behavior, & Immunity-Health, 2024 - Elsevier
Evidence suggests that neuroinflammation exhibits a dual role in the pathogenesis of major
depressive disorder (MDD), both potentiating the onset of depressive symptoms and …