Glycomics aims to identify the structure and function of the glycome, the complete set of
oligosaccharides (glycans), produced in a given cell or organism, as well as to identify …

Glycomic and glycoproteomic analyses involve the characterization of oligosaccharides
(glycans) conjugated to proteins. Glycans are produced through a complicated nontemplate …

Glycosylation is essential to brain development and function, but prior studies have often
been limited to a single analytical technique and excluded region-and sex-specific analyses …

While technologies for multiplexed imaging have provided an unprecedented understanding
of tissue composition in health and disease, interpreting this data remains a significant …

Mass spectrometry imaging (MSI) has gone through a significant change over the last 3
years, the time span of this review. The predominant mass spectrometric method in …

Background Within cells, there is a narrow concentration threshold that governs whether
reactive oxygen species (ROS) induce toxicity or act as second messengers. Scope of …

Glycosylation defects are a hallmark of many nervous system diseases. However, the
molecular and metabolic basis for this pathology is not fully understood. In this study, we …

Mass spectrometry is being used in many clinical research areas ranging from toxicology to
personalized medicine. Of all the mass spectrometry techniques, mass spectrometry …

The early detection of pancreatic ductal adenocarcinoma (PDAC) is a complex clinical
obstacle yet is key to improving the overall likelihood of patient survival. Current and …

A recently developed matrix-assisted laser desorption/ionization imaging mass spectrometry
(MALDI-IMS) method to spatially profile the location and distribution of multiple N-linked …