Toxicity of polyamines and their metabolic products
AE Pegg - Chemical research in toxicology, 2013 - ACS Publications
Polyamines are ubiquitous and essential components of mammalian cells. They have
multiple functions including critical roles in nucleic acid and protein synthesis, gene …
multiple functions including critical roles in nucleic acid and protein synthesis, gene …
Targeting polyamine metabolism for cancer therapy and prevention
TR Murray-Stewart, PM Woster… - Biochemical …, 2016 - portlandpress.com
The chemically simple, biologically complex eukaryotic polyamines, spermidine and
spermine, are positively charged alkylamines involved in many crucial cellular processes …
spermine, are positively charged alkylamines involved in many crucial cellular processes …
[HTML][HTML] Polyamine oxidases play various roles in plant development and abiotic stress tolerance
Z Yu, D Jia, T Liu - Plants, 2019 - mdpi.com
Polyamines not only play roles in plant growth and development, but also adapt to
environmental stresses. Polyamines can be oxidized by copper-containing diamine …
environmental stresses. Polyamines can be oxidized by copper-containing diamine …
[HTML][HTML] The involvement of polyamines catabolism in the crosstalk between neurons and astrocytes in neurodegeneration
In mammalian cells, the content of polyamines is tightly regulated. Polyamines, including
spermine, spermidine and putrescine, are involved in many cellular processes. Spermine …
spermine, spermidine and putrescine, are involved in many cellular processes. Spermine …
Transcriptomics and metabolomics reveal Ca2+ overload and osmotic imbalance-induced neurotoxicity in earthworms (Eisenia fetida) under tri-n-butyl phosphate …
X Jiang, Y Yang, P Liu, M Li - Science of the Total Environment, 2020 - Elsevier
Tri-n-butyl phosphate (TNBP) is mass-produced and widely utilized in many products, which
has increasingly drawn concern about its potential environmental risks. However, little is …
has increasingly drawn concern about its potential environmental risks. However, little is …
Polyamines metabolism and breast cancer: state of the art and perspectives
M Cervelli, S Pietropaoli, F Signore… - Breast cancer research …, 2014 - Springer
Breast cancer (BC) is a common disease that generally occurs in women over the age of 50,
and the risk is especially high for women over 60 years of age. One of the major BC …
and the risk is especially high for women over 60 years of age. One of the major BC …
Pharmacological potential of biogenic amine–polyamine interactions beyond neurotransmission
F Sánchez‐Jiménez, MV Ruiz‐Pérez… - British Journal of …, 2013 - Wiley Online Library
Histamine, serotonin and dopamine are biogenic amines involved in intercellular
communication with multiple effects on human pathophysiology. They are products of two …
communication with multiple effects on human pathophysiology. They are products of two …
Supplementation with spermine during in vitro maturation of porcine oocytes improves early embryonic development after parthenogenetic activation and somatic cell …
Spermine plays an important role in protection from reactive oxygen species (ROS) in
bacteria, yeast, and mammalian cells, but there are few studies on the effects of spermine on …
bacteria, yeast, and mammalian cells, but there are few studies on the effects of spermine on …
[HTML][HTML] Transgenic mouse overexpressing Spermine oxidase in Cerebrocortical neurons: astrocyte dysfunction and susceptibility to epileptic seizures
Polyamines are organic polycations ubiquitously present in living cells. Polyamines are
involved in many cellular processes, and their content in mammalian cells is tightly …
involved in many cellular processes, and their content in mammalian cells is tightly …
[HTML][HTML] Metabolomic Reprogramming of C57BL/6-Macrophages during Early Infection with L. amazonensis
M Mamani-Huanca, SM Muxel, SM Acuña… - International Journal of …, 2021 - mdpi.com
Leishmania survival inside macrophages depends on factors that lead to the immune
response evasion during the infection. In this context, the metabolic scenario of the host cell …
response evasion during the infection. In this context, the metabolic scenario of the host cell …