The advantages of the model organism Drosophila melanogaster, including low genetic
redundancy, functional simplicity, and the ability to conduct large-scale genetic screens …

Circadian clocks organize behavior and physiology to adapt to daily environmental cycles.
Genetic approaches in the fruit fly, Drosophila melanogaster, have revealed widely …

Employing the clear, student-friendly style that made previous editions so popular, Insect
Physiology and Biochemistry, Fourth Edition presents an engaging and authoritative guide …

Research in the fruit fly Drosophila melanogaster has led to insights in neural development,
axon guidance, ion channel function, synaptic transmission, learning and memory, diurnal …

A genetic screen for mutants that alter circadian rhythms in Drosophila identified the first
clock gene—the period (per) gene. The per gene is a central player within a transcriptional …

The plant circadian clock is proposed to be a network of several interconnected feedback
loops, and loss of any component leads to changes in oscillator speed. We previously …

The mammalian circadian clockwork is composed of a core PER/CRY feedback loop and
additional interlocking loops. In particular, the ROR/REV/Bmal1 loop, consisting of ROR …

Most organisms possess time-keeping devices called circadian clocks. At the molecular
level, circadian clocks consist of transcription–translation feedback loops (TTFLs). Although …

Systematic genetic approaches have provided deep insight into the molecular and cellular
mechanisms that operate in simple unicellular organisms. For multicellular organisms …

Nowadays humans mainly rely on external, unnatural clocks such as of cell phones and
alarm clocks–driven by circuit boards and electricity. Nevertheless, our body is under the …