Galectins are carbohydrate-binding proteins that are involved in many physiological
functions, such as inflammation, immune responses, cell migration, autophagy and …

Early disruptions to neurodevelopment are highly relevant to understanding both psychiatric
risk and underlying pathophysiology that can be targeted by new treatments. Much …

The dynamics of the chromatin regulatory landscape during human early embryogenesis
remains unknown. Using DNase I hypersensitive site (DHS) sequencing, we report that the …

The placenta is one of the organs with the highest evolutionary diversity among animal
species. In consequence, an animal model that reflects human placentation exactly does not …

Preeclampsia is a disease of the mother, fetus, and placenta, and the gaps in our
understanding of the complex interactions among their respective disease pathways …

In humans, cell fusion is restricted to only a few cell types under normal conditions. In the
placenta, cell fusion is a critical process for generating syncytiotrophoblast: the giant …

Galectins are β‐galcotosid‐binding lectins. The function of galectins varies with their tissue‐
specific and subcellular location, and their binding to carbohydrates makes them key players …

Fusion of the trophoblast-derived choriocarcinoma cell line BeWo can be triggered by
forskolin. BeWo cells are regularly used as a cell culture model to mimic in vivo …

Although the precise pathophysiology of pre-eclampsia remains unknown, this condition
continues to be a major cause of maternal and fetal mortality. Early prediction of pre …

Galectins are a large family of carbohydrate binding proteins with members in nearly every
lineage of multicellular life. Through tandem and en-mass genome duplications, over 15 …