[HTML][HTML] Complement receptors and their role in leukocyte recruitment and phagocytosis
S Vandendriessche, S Cambier, P Proost… - Frontiers in Cell and …, 2021 - frontiersin.org
The complement system is deeply embedded in our physiology and immunity. Complement
activation generates a multitude of molecules that converge simultaneously on the …
activation generates a multitude of molecules that converge simultaneously on the …
[HTML][HTML] β2 integrins as regulators of dendritic cell, monocyte, and macrophage function
L Schittenhelm, CM Hilkens, VL Morrison - Frontiers in immunology, 2017 - frontiersin.org
Emerging evidence suggests that the β 2 integrin family of adhesion molecules have an
important role in suppressing immune activation and inflammation. β 2 integrins are …
important role in suppressing immune activation and inflammation. β 2 integrins are …
Material stiffness influences the polarization state, function and migration mode of macrophages
Biomaterial implantation is followed by an inflammatory cascade dominated by
macrophages, which determine implant acceptance or rejection through pro-and anti …
macrophages, which determine implant acceptance or rejection through pro-and anti …
The role of CR3 (CD11b/CD18) and CR4 (CD11c/CD18) in complement-mediated phagocytosis and podosome formation by human phagocytes
CR3 and CR4 belong to the family of β 2-integrins and play an important role in
phagocytosis, cellular adherence and migration. CR3 and CR4 are generally expected to …
phagocytosis, cellular adherence and migration. CR3 and CR4 are generally expected to …
Choroidal endothelial and macrophage gene expression in atrophic and neovascular macular degeneration
The human choroid is a heterogeneous, highly vascular connective tissue that dysfunctions
in age-related macular degeneration (AMD). In this study, we performed single-cell RNA …
in age-related macular degeneration (AMD). In this study, we performed single-cell RNA …
A practical review on the measurement tools for cellular adhesion force
Cell–cell and cell–matrix adhesions are fundamental in all multicellular organisms. They
play a key role in cellular growth, differentiation, pattern formation and migration. Cell-cell …
play a key role in cellular growth, differentiation, pattern formation and migration. Cell-cell …
Interferon regulatory factor 5 controls necrotic core formation in atherosclerotic lesions by impairing efferocytosis
AN Seneviratne, A Edsfeldt, JE Cole, C Kassiteridi… - Circulation, 2017 - Am Heart Assoc
Background: Myeloid cells are central to atherosclerotic lesion development and vulnerable
plaque formation. Impaired ability of arterial phagocytes to uptake apoptotic cells …
plaque formation. Impaired ability of arterial phagocytes to uptake apoptotic cells …
[HTML][HTML] Biomechanical contributions to macrophage activation in the tumor microenvironment
EJ Hoffmann, SM Ponik - Frontiers in Oncology, 2020 - frontiersin.org
Alterations in extracellular matrix composition and organization are known to promote tumor
growth and metastatic progression in breast cancer through interactions with tumor cells as …
growth and metastatic progression in breast cancer through interactions with tumor cells as …
[HTML][HTML] New aspects in the regulation of human B cell functions by complement receptors CR1, CR2, CR3 and CR4
The involvement of complement in the regulation of antibody responses has been known for
long. By now several additional B cell functions–including cytokine production and antigen …
long. By now several additional B cell functions–including cytokine production and antigen …
[HTML][HTML] Alzheimer's genes in microglia: a risk worth investigating
A Sudwarts, G Thinakaran - Molecular Neurodegeneration, 2023 - Springer
Despite expressing many key risk genes, the role of microglia in late-onset Alzheimer's
disease pathophysiology is somewhat ambiguous, with various phenotypes reported to be …
disease pathophysiology is somewhat ambiguous, with various phenotypes reported to be …