Abstract 4D multi-image-based (4D MIB) optimization is a form of robust optimization where
different uncertainty scenarios, due to anatomy variations, are considered via multiple image …

Compared to conventional radiotherapy using X-rays, proton therapy, in principle, allows
better conformity of the dose distribution to target volumes, at the cost of greater sensitivity to …

Abstract The Danish Prostate Cancer Group is launching the randomized trial, PROstate
PROTON Trial 1 (NCT05350475), that compares photons and protons to the prostate and …

Introduction: Density changes occurring during fractionated radiotherapy in the pelvic region
may degrade proton dose distributions. The aim of the study was to quantify the dosimetric …

Purpose Proton therapy of moving targets is considered a challenge. At Maastro, we started
treating lung cancer patients with proton therapy in October 2019. In this work, we …

Simple Summary The manuscript discusses the administration of proton therapy to the first
13 pediatric patients in the prospective SJWT21 clinical trial to assess the efficacy of proton …

Purpose To evaluate the feasibility of using on‐treatment magnetic resonance imaging
(MRI) to detect proton range changes during treatment courses. Methods MRI‐based virtual …

Introduction. Internal organ motion and deformations may cause dose degradations in
proton therapy (PT) that are challenging to resolve using conventional image-guidance …

Purpose Intensity modulated proton therapy (IMPT) of locally advanced prostate cancer can
spare the bowel considerably compared with modern photon therapy, but simultaneous …

Purpose Pelvic target dose from intensity-modulated proton therapy (IMPT) is sensitive to
patient bowel motion. Robustly optimized plans in regard to bowel filling may improve the …