Purinergic regulation of endothelial barrier function
Increased vascular permeability is a hallmark of several cardiovascular anomalies, including
ischaemia/reperfusion injury and inflammation. During both ischaemia/reperfusion and …
ischaemia/reperfusion injury and inflammation. During both ischaemia/reperfusion and …
Increased signaling via adenosine A1 receptors, sleep deprivation, imipramine, and ketamine inhibit depressive-like behavior via induction of Homer1a
T Serchov, HW Clement, MK Schwarz, F Iasevoli… - Neuron, 2015 - cell.com
Major depressive disorder is among the most commonly diagnosed disabling mental
diseases. Several non-pharmacological treatments of depression upregulate adenosine …
diseases. Several non-pharmacological treatments of depression upregulate adenosine …
Signaling pathways regulating Homer1a expression: implications for antidepressant therapy
Homer1a is upregulated by several different antidepressant measures, including non-
pharmacological treatments, like sleep deprivation (SD) and electroconvulsive therapy …
pharmacological treatments, like sleep deprivation (SD) and electroconvulsive therapy …
Regulation of circadian genes by the MAPK pathway: implications for rapid antidepressant action
XL Wang, K Yuan, W Zhang, SX Li, GF Gao, L Lu - Neuroscience bulletin, 2020 - Springer
Accumulating evidence suggests that the circadian rhythm plays a critical role in mood
regulation, and circadian disturbances are often found in patients with major depressive …
regulation, and circadian disturbances are often found in patients with major depressive …
A1 Adenosine Receptor Activation Modulates Central Nervous System Development and Repair
S Kashfi, K Ghaedi, H Baharvand… - Molecular …, 2017 - Springer
Adenosine is an endogenous, autacoid purine nucleoside which performs many important
biological roles, particularly during stressful events. Adenosine can signal through four …
biological roles, particularly during stressful events. Adenosine can signal through four …
Activation of transient receptor potential canonical 3 (TRPC3)-mediated Ca2+ entry by A1 adenosine receptor in cardiomyocytes disturbs atrioventricular conduction
J Sabourin, F Antigny, E Robin, M Frieden… - Journal of Biological …, 2012 - ASBMB
Although the activation of the A 1-subtype of the adenosine receptors (A 1 AR) is
arrhythmogenic in the developing heart, little is known about the underlying downstream …
arrhythmogenic in the developing heart, little is known about the underlying downstream …
Arrhythmias in the developing heart
D Sedmera, R Kockova, F Vostarek… - Acta …, 2015 - Wiley Online Library
Prevalence of cardiac arrhythmias increases gradually with age; however, specific rhythm
disturbances can appear even prior to birth and markedly affect foetal development …
disturbances can appear even prior to birth and markedly affect foetal development …
Activating adenosine A1 receptor accelerates PC12 cell injury via ADORA1/PKC/KATP pathway after intermittent hypoxia exposure
HF Mei, N Poonit, YC Zhang, CY Ye, HL Cai… - Molecular and cellular …, 2018 - Springer
Obstructive sleep apnea hypopnea syndrome (OSAHS) is associated with the
neurocognitive deficits as a result of the neuronal cell injury. Previous studies have shown …
neurocognitive deficits as a result of the neuronal cell injury. Previous studies have shown …
Pharmacology of ectonucleotidases: relevance for the treatment of cardiovascular disorders
P Mathieu - European journal of pharmacology, 2012 - Elsevier
ATP and other extracellular nucleotides have diverse and potent effects in different organs.
Evidence indicates that extracellular nucleotides and nucleosides deliver crucial signals by …
Evidence indicates that extracellular nucleotides and nucleosides deliver crucial signals by …
Pacing-induced regional differences in adenosine receptors mRNA expression in a swine model of dilated cardiomyopathy
The adenosinergic system is essential in the mediation of intrinsic protection and myocardial
resistance to insult; it may be considered a cardioprotective molecule and adenosine …
resistance to insult; it may be considered a cardioprotective molecule and adenosine …