Fertility preservation for prepubertal boys: lessons learned from the past and update on remaining challenges towards clinical translation
BACKGROUND Childhood cancer incidence and survivorship are both on the rise.
However, many lifesaving treatments threaten the prepubertal testis. Cryopreservation of …
However, many lifesaving treatments threaten the prepubertal testis. Cryopreservation of …
Fertility preservation for prepubertal boys: are we ready for autologous grafting of cryopreserved immature testicular tissue?
Fertility preservation in prepubertal boys is a matter that has been gaining ground fast during
the past 20 years. As the life expectancy for childhood cancer survivors continues to …
the past 20 years. As the life expectancy for childhood cancer survivors continues to …
Long-term follow-up to assess criteria for ovarian tissue cryopreservation for fertility preservation in young women and girls with cancer
Abstract STUDY QUESTION Do the Edinburgh Selection Criteria correctly identify female
cancer patients under the age of 18 who are at risk of premature ovarian insufficiency (POI) …
cancer patients under the age of 18 who are at risk of premature ovarian insufficiency (POI) …
[HTML][HTML] A dozen years of ovarian tissue cryopreservation at a pediatric hospital: tracking program and patient metrics while adapting to increasing needs
KL McElhinney, T Kennedy, EE Rowell, MM Laronda - F&S Reports, 2024 - Elsevier
Objective To review the program and patient metrics for ovarian tissue cryopreservation
(OTC) within a comprehensive pediatric fertility preservation program in its first 12 years of …
(OTC) within a comprehensive pediatric fertility preservation program in its first 12 years of …
[HTML][HTML] In Vitro Generation of Haploid Germ Cells from Human XY and XXY Immature Testes in a 3D Organoid System
G Galdon, NP Zarandi, NA Deebel, S Zhang, O Cornett… - Bioengineering, 2024 - mdpi.com
Increasing survival rates of children following cancer treatment have resulted in a significant
population of adult survivors with the common side effect of infertility. Additionally, the …
population of adult survivors with the common side effect of infertility. Additionally, the …
[HTML][HTML] Dissociation, enrichment, and the in vitro formation of gonocyte colonies from cryopreserved neonatal bovine testicular tissues
Gonocytes play an important role in early development of spermatogonial stem cells and
fertility preservation to acquire more high quality gonocytes in vitro for further germ cell …
fertility preservation to acquire more high quality gonocytes in vitro for further germ cell …
Strategies for cryopreservation of testicular cells and tissues in cancer and genetic diseases
Cryopreservation of testicular cells and tissues is useful for the preservation and restoration
of fertility in pre-pubertal males expecting gonadotoxic treatment for cancer and genetic …
of fertility in pre-pubertal males expecting gonadotoxic treatment for cancer and genetic …
Comparison of two culture methods during in vitro spermatogenesis of vitrified-warmed testis tissue: Organ culture vs. hanging drop culture
Solid surface vitrification (SSV) is a cost effective and simple method for testis tissue
preservation. Vitrified-warmed testis tissue was successfully cultured using various organ …
preservation. Vitrified-warmed testis tissue was successfully cultured using various organ …
[HTML][HTML] Determining the optimal time interval between sample acquisition and cryopreservation when processing immature testicular tissue to preserve fertility
The cryopreservation of immature testicular tissue (ITT) prior to gonadotoxic therapy is
crucial for fertility preservation in prepubertal boys with cancer. However, the optimal holding …
crucial for fertility preservation in prepubertal boys with cancer. However, the optimal holding …
Limited spermatogenic differentiation of testicular tissue from prepubertal marmosets (Callithrix jacchus) in an in vitro organ culture system
S Sharma, RS Klaverkamp, J Wistuba… - Molecular and Cellular …, 2022 - Elsevier
Purpose of the research: To achieve male fertility preservation and restoration, experimental
strategies for in vitro germ cell differentiation are required. The effects of two different culture …
strategies for in vitro germ cell differentiation are required. The effects of two different culture …