Multiple sources of evidence support a role for diminished dopaminergic neurotrans-mission
in major depression. The physiological alterations underlying reduced dopa-mine (DA) …

Stressful stimuli evoke complex endocrine, autonomic, and behavioral responses that are
extremely variable and specific depending on the type and nature of the stressors. We first …

To dissect the genetic architecture of blood pressure and assess effects on target organ
damage, we analyzed 128,272 SNPs from targeted and genome-wide arrays in 201,529 …

Post-traumatic stress disorder (PTSD) is increasingly recognized as both a disorder of
enormous mental health and societal burden, but also as an anxiety disorder that may be …

Executive control processes, such as sustained attention, response inhibition, and error
monitoring, allow humans to guide behavior in appropriate, flexible, and adaptive ways. The …

No pharmacotherapies are approved for stimulant use disorders, which are an important
public health problem. Stimulants increase synaptic levels of the monoamines dopamine …

Dopamine beta‐hydroxylase (DβH) is an essential neurotransmitter‐synthesizing enzyme
that catalyzes the formation of norepinephrine (NE) from dopamine and has been …

We describe the use of behavioral, neuroimaging, and genetic methods to examine
individual differences in cognition and affect, guided by three criteria:(1) relevance to human …

In the past decade, evidence for numerous roles of copper (Cu) in mammalian physiology
has grown exponentially. The discoveries of Cu involvement in cell signaling, autophagy …

The norepinephrine pathway is believed to modulate behavioral and physiological
processes, such as mood, overall arousal, and attention. Furthermore, abnormalities in the …