The radioresistant and survival mechanisms of Deinococcus radiodurans

F Liu, N Li, Y Zhang - Radiation Medicine and Protection, 2023 - mednexus.org
Deinococcus radiodurans (D. radiodurans) is distinguished by the most radioresistant
organism ever known, and can tolerate extreme environments such as ionizing radiation …

Insights into the synthesis, engineering, and functions of microbial pigments in Deinococcus bacteria

Y Wang, J Liu, Y Yi, L Zhu, M Liu, Z Zhang… - Frontiers in …, 2024 - frontiersin.org
The ability of Deinococcus bacteria to survive in harsh environments, such as high radiation,
extreme temperature, and dryness, is mainly attributed to the generation of unique pigments …

TMbed: transmembrane proteins predicted through language model embeddings

M Bernhofer, B Rost - BMC bioinformatics, 2022 - Springer
Background Despite the immense importance of transmembrane proteins (TMP) for
molecular biology and medicine, experimental 3D structures for TMPs remain about 4–5 …

Interdigitated immunoglobulin arrays form the hyperstable surface layer of the extremophilic bacterium Deinococcus radiodurans

A von Kügelgen, S van Dorst… - Proceedings of the …, 2023 - National Acad Sciences
Deinococcus radiodurans is an atypical diderm bacterium with a remarkable ability to
tolerate various environmental stresses, due in part to its complex cell envelope …

[HTML][HTML] Protein dynamics: The future is bright and complicated!

K Nam, M Wolf-Watz - Structural Dynamics, 2023 - pubs.aip.org
Biological life depends on motion, and this manifests itself in proteins that display motion
over a formidable range of time scales spanning from femtoseconds vibrations of atoms at …

The structured organization of Deinococcus radiodurans' cell envelope

D Farci, P Haniewicz, D Piano - Proceedings of the …, 2022 - National Acad Sciences
Surface layers (S-layers) are highly ordered coats of proteins localized on the cell surface of
many bacterial species. In these structures, one or more proteins form elementary units that …

Dual function of OmpM as outer membrane tether and nutrient uptake channel in diderm Firmicutes

A Silale, Y Zhu, J Witwinowski, RE Smith… - Nature …, 2023 - nature.com
The outer membrane (OM) in diderm, or Gram-negative, bacteria must be tethered to
peptidoglycan for mechanical stability and to maintain cell morphology. Most diderm phyla …

Antioxidant defense of Deinococcus radiodurans: how does it contribute to extreme radiation resistance?

I Sadowska-Bartosz, G Bartosz - International Journal of Radiation …, 2023 - Taylor & Francis
Purpose Deinococcus radiodurans is an extremely radioresistant bacterium characterized
by D10 of 10 kGy, and able to grow luxuriantly under chronic ionizing radiation of 60 Gy/h …

Structural characterization and functional insights into the type II secretion system of the poly-extremophile Deinococcus radiodurans

D Farci, S Milenkovic, L Iesu, M Tanas… - Journal of Biological …, 2024 - ASBMB
The extremophile bacterium D. radiodurans boasts a distinctive cell envelope characterized
by the regular arrangement of three protein complexes. Among these, the Type II Secretion …

The SDBC is active in quenching oxidative conditions and bridges the cell envelope layers in Deinococcus radiodurans

D Farci, AT Graça, L Iesu, D de Sanctis… - Journal of Biological …, 2023 - ASBMB
Deinococcus radiodurans is known for its remarkable ability to withstand harsh stressful
conditions. The outermost layer of its cell envelope is a proteinaceous coat, the S-layer …