COVID-19 vaccines: The status and perspectives in delivery points of view
Due to the high prevalence and long incubation periods often without symptoms, the severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has infected millions of individuals …
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has infected millions of individuals …
[HTML][HTML] Novel approaches for vaccine development
MS Gebre, LA Brito, LH Tostanoski, DK Edwards… - Cell, 2021 - cell.com
Vaccines are critical tools for maintaining global health. Traditional vaccine technologies
have been used across a wide range of bacterial and viral pathogens, yet there are a …
have been used across a wide range of bacterial and viral pathogens, yet there are a …
Accelerating the prediction and discovery of peptide hydrogels with human-in-the-loop
The amino acid sequences of peptides determine their self-assembling properties. Accurate
prediction of peptidic hydrogel formation, however, remains a challenging task. This work …
prediction of peptidic hydrogel formation, however, remains a challenging task. This work …
Nanoparticle-based delivery systems for vaccines
Vaccination is still the most cost-effective way to combat infectious illnesses. Conventional
vaccinations may have low immunogenicity and, in most situations, only provide partial …
vaccinations may have low immunogenicity and, in most situations, only provide partial …
Next‐generation vaccines: nanoparticle‐mediated DNA and mRNA delivery
Nucleic acid vaccines are a method of immunization aiming to elicit immune responses akin
to live attenuated vaccines. In this method, DNA or messenger RNA (mRNA) sequences are …
to live attenuated vaccines. In this method, DNA or messenger RNA (mRNA) sequences are …
Nanobiotics against antimicrobial resistance: harnessing the power of nanoscale materials and technologies
Given the spasmodic increment in antimicrobial resistance (AMR), world is on the verge of
“post-antibiotic era”. It is anticipated that current SARS-CoV2 pandemic would worsen the …
“post-antibiotic era”. It is anticipated that current SARS-CoV2 pandemic would worsen the …
Semiconducting polymer nanoparticles with surface‐mimicking protein secondary structure as lysosome‐targeting chimaeras for self‐synergistic cancer …
Immunotherapy has received tremendous attention for tumor treatment, but the efficacy is
greatly hindered by insufficient tumor‐infiltration of immune cells and immunosuppressive …
greatly hindered by insufficient tumor‐infiltration of immune cells and immunosuppressive …
A nanoadjuvant that dynamically coordinates innate immune stimuli activation enhances cancer immunotherapy and reduces immune cell exhaustion
SM Jin, YJ Yoo, HS Shin, S Kim, SN Lee… - Nature …, 2023 - nature.com
Although conventional innate immune stimuli contribute to immune activation, they induce
exhausted immune cells, resulting in suboptimal cancer immunotherapy. Here we suggest a …
exhausted immune cells, resulting in suboptimal cancer immunotherapy. Here we suggest a …
Immune imprinting and next-generation coronavirus vaccines
CQ Huang, S Vishwanath, GW Carnell, ACY Chan… - Nature …, 2023 - nature.com
Vaccines based on historical virus isolates provide limited protection from continuously
evolving RNA viruses, such as influenza viruses or coronaviruses, which occasionally spill …
evolving RNA viruses, such as influenza viruses or coronaviruses, which occasionally spill …
Gold nanoparticles (GNPs) in biomedical and clinical applications: A review
Gold nanoparticles (GNPs) have been extensively used in various applications ranging from
environmental detection to biomedical applications. Due to their unique characteristics such …
environmental detection to biomedical applications. Due to their unique characteristics such …