Whole‐genome sequencing is revolutionizing our understanding of organismal biology,
including adaptations likely to influence demographic performance in different …

We here present CLUES2, a full-likelihood method to infer natural selection from sequence
data that is an extension of the method CLUES. We make several substantial improvements …

Natural selection on beneficial or deleterious alleles results in an increase or decrease,
respectively, of their frequency within the population. Due to chromosomal linkage, the …

Kanker payudara merupakan masalah kesehatan yang serius, sehingga deteksi dini dari
kanker payudara dapat berperan penting dalam perencanaan pengobatan. Pada penelitian …

Interacting systems of events may exhibit cascading behavior where events tend to be
temporally clustered. While the cascades themselves may be obvious from the data, it is …

In this article, a biallelic reversible mutation model with linear and quadratic selection is
analysed. The approach reconnects to one proposed by Kimura (1979), who starts from a …

Stochastic evolution equations describing the dynamics of systems under the influence of
both deterministic and stochastic forces are prevalent in all fields of science. Yet, identifying …

In this article, discrete and stochastic changes in (effective) population size are incorporated
into the spectral representation of a biallelic diffusion process for drift and small mutation …

Inference of the marginal likelihood of sample allele configurations using backward
algorithms yields identical results with the Kingman coalescent, the Moran model, and the …

In population genetics, extant samples are usually used for inference of past population
genetic forces. With the Kingman coalescent and the backward diffusion equation, inference …