[HTML][HTML] The design of small-molecule prodrugs and activatable phototherapeutics for cancer therapy

HH Han, HM Wang, P Jangili, M Li, L Wu… - Chemical Society …, 2023 - pubs.rsc.org
Cancer remains as one of the most significant health problems, with approximately 19
million people diagnosed worldwide each year. Chemotherapy is a routinely used method to …

Near-infrared (NIR) fluorescence-emitting small organic molecules for cancer imaging and therapy

H Li, Y Kim, H Jung, JY Hyun, I Shin - Chemical Society Reviews, 2022 - pubs.rsc.org
Near-infrared (NIR) fluorophores have unique features that endow them with several
advantages over conventional shorter wavelength emitting dyes. As a result, they have been …

[HTML][HTML] Polymersome-based protein drug delivery–quo vadis?

MG Gouveia, JP Wesseler, J Ramaekers… - Chemical Society …, 2023 - pubs.rsc.org
Protein-based therapeutics are an attractive alternative to established therapeutic
approaches and represent one of the fastest growing families of drugs. While many of these …

Near‐Infrared‐II Plasmonic Trienzyme‐Integrated Metal–Organic Frameworks with High‐Efficiency Enzyme Cascades for Synergistic Trimodal Oncotherapy

G Zhou, M Li - Advanced Materials, 2022 - Wiley Online Library
Natural enzyme‐based catalytic cascades hold great promise for cancer therapy, but their
clinical utility is greatly hindered by the loss of their functions during in vivo delivery. Herein …

[HTML][HTML] Implications of insulin-like growth factor-1 in skeletal muscle and various diseases

SS Ahmad, K Ahmad, EJ Lee, YH Lee, I Choi - Cells, 2020 - mdpi.com
Skeletal muscle is an essential tissue that attaches to bones and facilitates body
movements. Insulin-like growth factor-1 (IGF-1) is a hormone found in blood that plays an …

The Fibrillin‐1/VEGFR2/STAT2 signaling axis promotes chemoresistance via modulating glycolysis and angiogenesis in ovarian cancer organoids and cells

Z Wang, W Chen, L Zuo, M Xu, Y Wu… - Cancer …, 2022 - Wiley Online Library
Background Chemotherapy resistance is a primary reason of ovarian cancer therapy failure;
hence it is important to investigate the underlying mechanisms of chemotherapy resistance …

Research progress on tumor hypoxia-associative nanomedicine

XX Xu, SY Chen, NB Yi, X Li, SL Chen, Z Lei… - Journal of Controlled …, 2022 - Elsevier
Hypoxia at the solid tumor site is generally related to the unrestricted proliferation and
metabolism of cancerous cells, which can cause tumor metastasis and aggravate tumor …

Strategies to reverse hypoxic tumor microenvironment for enhanced sonodynamic therapy

J Li, Z Yue, M Tang, W Wang, Y Sun… - Advanced Healthcare …, 2024 - Wiley Online Library
Sonodynamic therapy (SDT) has emerged as a highly effective modality for the treatment of
malignant tumors owing to its powerful penetration ability, noninvasiveness, site‐confined …

Ginger and its active compounds in cancer therapy: From folk uses to nano-therapeutic applications

MF Mahomoodally, MZ Aumeeruddy… - Seminars in cancer …, 2021 - Elsevier
Ginger is a spice that is renowned for its characteristic aromatic fragrance and pungent taste,
with documented healing properties. Field studies conducted in several Asian and African …

[HTML][HTML] Mesoporous silica nanoparticles: Properties and strategies for enhancing clinical effect

AN Frickenstein, JM Hagood, CN Britten, BS Abbott… - Pharmaceutics, 2021 - mdpi.com
Due to the theragnostic potential of mesoporous silica nanoparticles (MSNs), these were
extensively investigated as a novel approach to improve clinical outcomes. Boasting an …