Reactive oxygen species in macrophages: sources and targets
M Canton, R Sánchez-Rodríguez, I Spera… - Frontiers in …, 2021 - frontiersin.org
Reactive oxygen species (ROS) are fundamental for macrophages to eliminate invasive
microorganisms. However, as observed in nonphagocytic cells, ROS play essential roles in …
microorganisms. However, as observed in nonphagocytic cells, ROS play essential roles in …
Cellular and molecular pathobiology of heart failure with preserved ejection fraction
Heart failure with preserved ejection fraction (HFpEF) affects half of all patients with heart
failure worldwide, is increasing in prevalence, confers substantial morbidity and mortality …
failure worldwide, is increasing in prevalence, confers substantial morbidity and mortality …
Mitochondrial dysfunction and oxidative stress in heart disease
Beyond their role as a cellular powerhouse, mitochondria are emerging as integral players
in molecular signaling and cell fate determination through reactive oxygen species (ROS) …
in molecular signaling and cell fate determination through reactive oxygen species (ROS) …
The role of oxidative stress in cardiac disease: from physiological response to injury factor
R D'Oria, R Schipani, A Leonardini… - Oxidative medicine …, 2020 - Wiley Online Library
Reactive oxygen species (ROS) are highly reactive chemical species containing oxygen,
controlled by both enzymatic and nonenzymatic antioxidant defense systems. In the heart …
controlled by both enzymatic and nonenzymatic antioxidant defense systems. In the heart …
Mitochondrial ROS formation in the pathogenesis of diabetic cardiomyopathy
N Kaludercic, F Di Lisa - Frontiers in Cardiovascular Medicine, 2020 - frontiersin.org
Diabetic cardiomyopathy is a result of diabetes-induced changes in the structure and
function of the heart. Hyperglycemia affects multiple pathways in the diabetic heart, but …
function of the heart. Hyperglycemia affects multiple pathways in the diabetic heart, but …
Stroke–heart syndrome: recent advances and challenges
After ischemic stroke, there is a significant burden of cardiovascular complications, both in
the acute and chronic phase. Severe adverse cardiac events occur in 10% to 20% of …
the acute and chronic phase. Severe adverse cardiac events occur in 10% to 20% of …
Pathophysiological role of oxidative stress in systolic and diastolic heart failure and its therapeutic implications
Systolic and diastolic myocardial dysfunction has been demonstrated to be associated with
an activation of the circulating and local renin–angiotensin–aldosterone system (RAAS), and …
an activation of the circulating and local renin–angiotensin–aldosterone system (RAAS), and …
CVD and oxidative stress
K Cervantes Gracia, D Llanas-Cornejo… - Journal of clinical …, 2017 - mdpi.com
Nowadays, it is known that oxidative stress plays at least two roles within the cell, the
generation of cellular damage and the involvement in several signaling pathways in its …
generation of cellular damage and the involvement in several signaling pathways in its …
[HTML][HTML] Stress-induced biological aging: A review and guide for research priorities
LR Polsky, KE Rentscher, JE Carroll - Brain, behavior, and immunity, 2022 - Elsevier
Exposure to chronic adverse conditions, and the resultant activation of the neurobiological
response cascade, has been associated with an increased risk of early onset of age-related …
response cascade, has been associated with an increased risk of early onset of age-related …