Mechanical regulation of mesenchymal stem cell differentiation

AJ Steward, DJ Kelly - Journal of anatomy, 2015 - Wiley Online Library
Biophysical cues play a key role in directing the lineage commitment of mesenchymal stem
cells or multipotent stromal cells (MSC s), but the mechanotransductive mechanisms at play …

Stem cell mechanobiology and the role of biomaterials in governing mechanotransduction and matrix production for tissue regeneration

SM Naqvi, LM McNamara - Frontiers in bioengineering and …, 2020 - frontiersin.org
Mechanobiology has underpinned many scientific advances in understanding how
biophysical and biomechanical cues regulate cell behavior by identifying mechanosensitive …

Strategies to engineer tendon/ligament-to-bone interface: biomaterials, cells and growth factors

SF Tellado, ER Balmayor, M Van Griensven - Advanced drug delivery …, 2015 - Elsevier
Integration between tendon/ligament and bone occurs through a specialized tissue interface
called enthesis. The complex and heterogeneous structure of the enthesis is essential to …

Cytoskeletal and focal adhesion influences on mesenchymal stem cell shape, mechanical properties, and differentiation down osteogenic, adipogenic, and …

PS Mathieu, EG Loboa - Tissue Engineering Part B: Reviews, 2012 - liebertpub.com
Mesenchymal stem cells (MSCs) hold great potential for regenerative medicine and tissue-
engineering applications. They have multipotent differentiation capabilities and have been …

The guidance of stem cell differentiation by substrate alignment and mechanical stimulation

SD Subramony, BR Dargis, M Castillo, EU Azeloglu… - Biomaterials, 2013 - Elsevier
Mesenchymal stem cells (MSC) represent a promising and clinically relevant cell source for
tissue engineering applications. As such, guiding MSCs toward specific lineages and …

Mechanical stretching for tissue engineering: two-dimensional and three-dimensional constructs

BD Riehl, JH Park, IK Kwon, JY Lim - Tissue Engineering Part B …, 2012 - liebertpub.com
Mechanical cell stretching may be an attractive strategy for the tissue engineering of
mechanically functional tissues. It has been demonstrated that cell growth and differentiation …

Engineering three-dimensional cell mechanical microenvironment with hydrogels

G Huang, L Wang, SQ Wang, Y Han, J Wu… - …, 2012 - iopscience.iop.org
Cell mechanical microenvironment (CMM) significantly affects cell behaviors such as
spreading, migration, proliferation and differentiation. However, most studies on cell …

Physical stimulations for bone and cartilage regeneration

X Huang, R Das, A Patel, T Duc Nguyen - Regenerative engineering and …, 2018 - Springer
A wide range of techniques and methods are actively invented by clinicians and scientists
who are dedicated to the field of musculoskeletal tissue regeneration. Biological, chemical …

2010 Nicolas Andry Award: multipotent adult stem cells from adipose tissue for musculoskeletal tissue engineering

F Guilak, BT Estes, BO Diekman… - Clinical Orthopaedics …, 2010 - journals.lww.com
2010 Nicolas Andry Award: Multipotent Adult Stem Cells from... : Clinical Orthopaedics and
Related Research® 2010 Nicolas Andry Award: Multipotent Adult Stem Cells from Adipose …

Chip-based comparison of the osteogenesis of human bone marrow-and adipose tissue-derived mesenchymal stem cells under mechanical stimulation

SH Park, WY Sim, BH Min, SS Yang… - 2012 - journals.plos.org
Adipose tissue-derived stem cells (ASCs) are considered as an attractive stem cell source
for tissue engineering and regenerative medicine. We compared human bone marrow …