Nasopharyngeal carcinoma: an evolving paradigm
The past three decades have borne witness to many advances in the understanding of the
molecular biology and treatment of nasopharyngeal carcinoma (NPC), an Epstein–Barr virus …
molecular biology and treatment of nasopharyngeal carcinoma (NPC), an Epstein–Barr virus …
Treating head and neck cancer in the age of immunotherapy: a 2023 update
A Bhatia, B Burtness - Drugs, 2023 - Springer
Most patients diagnosed with head and neck squamous cell carcinoma (HNSCC) will
present with locally advanced disease, requiring multimodality therapy. While this approach …
present with locally advanced disease, requiring multimodality therapy. While this approach …
The Chinese Society of Clinical Oncology (CSCO) clinical guidelines for the diagnosis and treatment of nasopharyngeal carcinoma
LL Tang, YP Chen, CB Chen, MY Chen… - Cancer …, 2021 - Wiley Online Library
Nasopharyngeal carcinoma (NPC) is a malignant epithelial tumor originating in the
nasopharynx and has a high incidence in Southeast Asia and North Africa. To develop these …
nasopharynx and has a high incidence in Southeast Asia and North Africa. To develop these …
Chemotherapy in combination with radiotherapy for definitive-intent treatment of stage II-IVA nasopharyngeal carcinoma: CSCO and ASCO guideline
YP Chen, N Ismaila, MLK Chua, AD Colevas… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE The aim of this joint guideline is to provide evidence-based recommendations to
practicing physicians and other healthcare providers on definitive-intent chemoradiotherapy …
practicing physicians and other healthcare providers on definitive-intent chemoradiotherapy …
WTAP-mediated m6A modification of lncRNA DIAPH1-AS1 enhances its stability to facilitate nasopharyngeal carcinoma growth and metastasis
ZX Li, ZQ Zheng, PY Yang, L Lin, GQ Zhou… - Cell Death & …, 2022 - nature.com
As the most predominant RNA epigenetic regulation in eukaryotic cells, N6-
methyladenosine (m6A) plays a critical role in human tumorigenesis and cancer …
methyladenosine (m6A) plays a critical role in human tumorigenesis and cancer …
Gemcitabine and cisplatin induction chemotherapy in nasopharyngeal carcinoma
Background Platinum-based concurrent chemoradiotherapy is the standard of care for
patients with locoregionally advanced nasopharyngeal carcinoma. Additional gemcitabine …
patients with locoregionally advanced nasopharyngeal carcinoma. Additional gemcitabine …
Metronomic capecitabine as adjuvant therapy in locoregionally advanced nasopharyngeal carcinoma: a multicentre, open-label, parallel-group, randomised …
YP Chen, X Liu, Q Zhou, KY Yang, F Jin, XD Zhu, M Shi… - The Lancet, 2021 - thelancet.com
Background Patients with locoregionally advanced nasopharyngeal carcinoma have a high
risk of disease relapse, despite a high proportion of patients attaining complete clinical …
risk of disease relapse, despite a high proportion of patients attaining complete clinical …
[HTML][HTML] Tumour heterogeneity and intercellular networks of nasopharyngeal carcinoma at single cell resolution
The heterogeneous nature of tumour microenvironment (TME) underlying diverse treatment
responses remains unclear in nasopharyngeal carcinoma (NPC). Here, we profile 176,447 …
responses remains unclear in nasopharyngeal carcinoma (NPC). Here, we profile 176,447 …
NCCN guidelines insights: head and neck cancers, version 1.2018
AD Colevas, SS Yom, DG Pfister, S Spencer… - Journal of the National …, 2018 - jnccn.org
The NCCN Guidelines for Head and Neck (H&N) Cancers provide treatment
recommendations for cancers of the lip, oral cavity, pharynx, larynx, ethmoid and maxillary …
recommendations for cancers of the lip, oral cavity, pharynx, larynx, ethmoid and maxillary …
Long noncoding RNA FAM225A promotes nasopharyngeal carcinoma tumorigenesis and metastasis by acting as ceRNA to sponge miR-590-3p/miR-1275 and …
ZQ Zheng, ZX Li, GQ Zhou, L Lin, LL Zhang, JW Lv… - Cancer research, 2019 - AACR
Long noncoding RNAs (lncRNA) play important roles in the tumorigenesis and progression
of cancers. However, the clinical significance of lncRNAs and their regulatory mechanisms …
of cancers. However, the clinical significance of lncRNAs and their regulatory mechanisms …