A compendium of global gene expression measurements from DNA microarray analysis of
immune cells identifies gene expression signatures defining various lineages, differentiation …

The number of intrinsically disordered proteins known to be involved in cell-signaling and
regulation is growing rapidly. To test for a generalized involvement of intrinsic disorder in …

T cell receptor (TCR) antigen recognition induces the formation of a specialized
'immunological synapse'at the T cell: antigen presenting cell (APC) junction. This junction is …

The hallmarks of the immune response to viral infections are the expansion of antigen-
specific CD8+ cytotoxic T lymphocytes (CTLs) after they encounter antigen-presenting cells …

During the interaction of a T cell with an antigen-presenting cell (APC), several receptor
ligand pairs, including the T cell receptor (TCR)/major histocompatibility complex (MHC) …

Reorganization of the actin cytoskeleton is crucial to the formation and function of the
immunological synapse. Rho GTPases are critical mediators of cytoskeletal reorganization …

Human CD2 regulates T cell activation and adhesion via mechanisms yet to be fully
understood. This study focuses on CD2BP1, a CD2 cytoplasmic tail-binding protein …

The activity of cofilin, an actin-remodeling protein, is required for T lymphocyte activation
with regard to formation of the immunological synapse, cytokine production, and …

The haematopoietic‐specific RhoGTPase, Rac2, has been indirectly implicated in T‐
lymphocyte development and function, and as a pivotal regulator of T Helper 1 (TH1) …

The aim of this review is to introduce the advances made over the past several years
regarding the participation of actin and actin-associated proteins in clathrin-mediated …