Therapeutic potential of oxadiazole or furadiazole containing compounds
As we know that, Oxadiazole or furadi azole ring containing derivatives are an important
class of heterocyclic compounds. A heterocyclic five-membered ring that possesses two …
class of heterocyclic compounds. A heterocyclic five-membered ring that possesses two …
1, 3, 4-Oxadiazole containing compounds as therapeutic targets for cancer therapy
MJ Ahsan - Mini Reviews in Medicinal Chemistry, 2022 - ingentaconnect.com
Background: Cancer is the first or second leading cause of premature death in 134 of 183
countries in the world. 1, 3, 4-Oxadiazoles are five membered heterocyclic rings containing …
countries in the world. 1, 3, 4-Oxadiazoles are five membered heterocyclic rings containing …
In silico and in vitro prediction of new synthesized N-heterocyclic compounds as anti-SARS-CoV-2
Computer-aided drug design has been employed to get the medicinal effects against
Corona virus from different pyridine derivatives after synthesizing the new compounds …
Corona virus from different pyridine derivatives after synthesizing the new compounds …
Design, Synthesis, ADME, and Anticancer Studies of Newer N-Aryl-5-(3,4,5-Trifluorophenyl)-1,3,4-Oxadiazol-2-Amines: An Insight into Experimental and Theoretical …
In continuance of our investigation into the anticancer activity of oxadiazoles, we report here
the preparation of 10 new 1, 3, 4-oxadiazole analogues using the scaffold hopping …
the preparation of 10 new 1, 3, 4-oxadiazole analogues using the scaffold hopping …
Tandem synthesis, cytotoxicity, and in silico study of new 1, 3, 4‐oxadiazoles as potential thymidylate synthase inhibitors
A new series of pyrrole‐linked mono‐and bis (1, 3, 4‐oxadiazole) hybrids, attached to
various arene units, was prepared using a two‐step tandem protocol. Therefore, a …
various arene units, was prepared using a two‐step tandem protocol. Therefore, a …
Synthesis of designed new 1, 3, 4-oxadiazole functionalized pyrano [2, 3-f] chromene derivatives and their antimicrobial activities
Abstract Diethyl 2-(((4-methyl-2-oxo-2H-chromen-7-yl) oxy) methylene) malonate (2) was
synthesized from coumarin 1 and diethyl ethoxymethylene malonate in ethanol, followed by …
synthesized from coumarin 1 and diethyl ethoxymethylene malonate in ethanol, followed by …
Synthesis, characterisation and evaluation of oxadiazole as promising anticancer agent
SV Mamatha, SL Belagali, M Bhat - SN Applied Sciences, 2020 - Springer
A unique series oxadiazoles were synthesized by cyclization of benzophenone hydrazide,
followed by the nucleophillic alkylation of heterocyclic scaffold. Synthesized title compounds …
followed by the nucleophillic alkylation of heterocyclic scaffold. Synthesized title compounds …
Ultrasound promoted green synthesis, anticancer evaluation, and molecular docking studies of hydrazines: a pilot trial
We reported herein an efficient, environmentally friendly synthesis of hydrazine
carboxamides (6a–l) in a water-glycerol (6: 4) solvent system using ultrasonic irradiation …
carboxamides (6a–l) in a water-glycerol (6: 4) solvent system using ultrasonic irradiation …
Design, synthesis and biological activity of novel oxadiazole containing monoacylglycerols as potential bioactive lipids
B Gandhi, M Jhansi, SS Deshpande, T Vinay… - Journal of Molecular …, 2023 - Elsevier
Abstract A series of novel 1, 3, 4-oxadiazole based 1-monoacylglycerol derivatives were
synthesized and evaluated for their antimicrobial and anticancer activity. Eight different …
synthesized and evaluated for their antimicrobial and anticancer activity. Eight different …
Synthesis, Identification, and Study of the Antimicrobial and Antioxidant Activities of Some New 2, 5-Disubstituted-1, 3, 4-Oxadiazole Derivatives
This study includes the synthesis of 2, 5-disubstituted-1, 3, 4-oxadiazole 3-12 on creatinine
derivatives that have antioxidant and microbial properties. The reaction of creatinine with …
derivatives that have antioxidant and microbial properties. The reaction of creatinine with …