Superoxide dismutases and superoxide reductases

Y Sheng, IA Abreu, DE Cabelli, MJ Maroney… - Chemical …, 2014 - ACS Publications
Superoxide, O2•−, is formed in all living organisms that come in contact with air, and,
depending upon its biological context, it may act as a signaling agent, a toxic species, or a …

Progress in Ab Initio QM/MM Free-Energy Simulations of Electrostatic Energies in Proteins: Accelerated QM/MM Studies of pKa, Redox Reactions and Solvation …

SCL Kamerlin, M Haranczyk… - The journal of physical …, 2009 - ACS Publications
Hybrid quantum mechanical/molecular mechanical (QM/MM) approaches have been used
to provide a general scheme for chemical reactions in proteins. However, such approaches …

New mechanistic insights into halogen-dependent cytotoxic pattern of monohaloacetamide disinfection byproducts

S Hu, X Li, T Gong, G Tian, S Guo, C Huo, J Wan… - Journal of Hazardous …, 2024 - Elsevier
As highly toxic nitrogenous disinfection byproducts (DBPs), monohaloacetamides
(monoHAcAms) generally exhibited a cytotoxic rank order of iodoacetamide˃ …

An overview of copper complexes with diamine-based N4 donor bis-pyridine Schiff base ligands: Synthesis, structures, magnetic properties and applications

S Pramanik, S Chattopadhyay - Inorganica Chimica Acta, 2023 - Elsevier
Different synthetic routes and structures of several copper complexes with several diamine-
based N 4 donor bis-pyridine Schiff base ligands have been gathered. Their structures and …

Hydrogen sulfide functions as a micro-modulator bound at the copper active site of Cu/Zn-SOD to regulate the catalytic activity of the enzyme

DD Wu, S Jin, RX Cheng, WJ Cai, WL Xue, QQ Zhang… - Cell Reports, 2023 - cell.com
The present study examines whether there is a mechanism beyond the current concept of
post-translational modifications to regulate the function of a protein. A small gas molecule …

Comparative genomics of trace elements: emerging dynamic view of trace element utilization and function

Y Zhang, VN Gladyshev - Chemical reviews, 2009 - ACS Publications
Biological trace elements are needed in minute quantities forpropergrowth, development,
andphysiologyoforganisms. 1r3 These micronutrients include iron (Fe), zinc (Zn), copper …

Structure and antioxidant superoxide dismutase activity of copper (II) hydrazone complexes

YP Singh, RN Patel, Y Singh, RJ Butcher… - Polyhedron, 2017 - Elsevier
Three new mixed ligand hydrazone complexes viz.,[Cu (L)(neocuprin)] NO 3· H 2 O 1,[Cu
(L)(HL)] ClO 4 2 and [Cu 2 (2-(2-pyridyl) benzimidazole) 2 (L) 2] ClO 4 3 (L= N′-[(E)-phenyl …

Nickel superoxide dismutase reaction mechanism studied by hybrid density functional methods

V Pelmenschikov, PEM Siegbahn - Journal of the American …, 2006 - ACS Publications
The reaction mechanism for the disproportionation of the toxic superoxide radical to
molecular oxygen and hydrogen peroxide by the nickel-dependent superoxide dismutase …

Redox Processes Involving Oxygen: The Surprising Influence of Redox-Inactive Lewis Acids

D Lionetti, S Suseno, AA Shiau, G de Ruiter, T Agapie - JACS Au, 2024 - ACS Publications
Metalloenzymes with heteromultimetallic active sites perform chemical reactions that control
several biogeochemical cycles. Transformations catalyzed by such enzymes include …

The protective effects of selenium and boron on cyclophosphamide-induced hepatic oxidative stress, inflammation, and apoptosis in rats

M Cengiz, B Gür, F Gür, V Şahintürk, A Bayrakdar… - Heliyon, 2024 - cell.com
Cyclophosphamide (CP) is an alkylating anticancer drug with broad clinical application that
is highly effective in the treatment of cancer and non-malignant diseases. However, the main …