[HTML][HTML] Cerebral dysfunctions caused by sepsis during ageing
T Manabe, MT Heneka - Nature Reviews Immunology, 2022 - nature.com
Systemic inflammation elicited by sepsis can induce an acute cerebral dysfunction known as
sepsis-associated encephalopathy (SAE). Recent evidence suggests that SAE is common …
sepsis-associated encephalopathy (SAE). Recent evidence suggests that SAE is common …
Sepsis therapies: learning from 30 years of failure of translational research to propose new leads
Sepsis has been identified by the World Health Organization (WHO) as a global health
priority. There has been a tremendous effort to decipher underlying mechanisms …
priority. There has been a tremendous effort to decipher underlying mechanisms …
Dexmedetomidine attenuates sepsis-associated inflammation and encephalopathy via central α2A adrenoceptor
B Mei, J Li, Z Zuo - Brain, Behavior, and Immunity, 2021 - Elsevier
Sepsis-associated encephalopathy (SAE) is a significant clinical issue that is associated
with increased mortality and cost of health care. Dexmedetomidine, an α2 adrenoceptor …
with increased mortality and cost of health care. Dexmedetomidine, an α2 adrenoceptor …
[HTML][HTML] Sepsis-associated encephalopathy: from delirium to dementia?
HY Chung, J Wickel, FM Brunkhorst, C Geis - Journal of clinical medicine, 2020 - mdpi.com
Sepsis is a major cause of death in intensive care units worldwide. The acute phase of
sepsis is often accompanied by sepsis-associated encephalopathy, which is highly …
sepsis is often accompanied by sepsis-associated encephalopathy, which is highly …
[HTML][HTML] Sepsis-associated brain injury: underlying mechanisms and potential therapeutic strategies for acute and long-term cognitive impairments
N Sekino, M Selim, A Shehadah - Journal of Neuroinflammation, 2022 - Springer
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to
infection. Sepsis causes cerebral dysfunction in the short and long term and induces …
infection. Sepsis causes cerebral dysfunction in the short and long term and induces …
Sepsis‐induced brain dysfunction: pathogenesis, diagnosis, and treatment
S Pan, Z Lv, R Wang, H Shu, S Yuan… - … medicine and cellular …, 2022 - Wiley Online Library
Dysregulated host response to infection, which cause life‐threatening organ dysfunction,
was defined as sepsis. Sepsis can cause acute and long‐term brain dysfunction, namely …
was defined as sepsis. Sepsis can cause acute and long‐term brain dysfunction, namely …
Microglia mediate neurocognitive deficits by eliminating C1q-tagged synapses in sepsis-associated encephalopathy
HY Chung, J Wickel, N Hahn, N Mein… - Science …, 2023 - science.org
Sepsis-associated encephalopathy (SAE) is a severe and frequent complication of sepsis
causing delirium, coma, and long-term cognitive dysfunction. We identified microglia and …
causing delirium, coma, and long-term cognitive dysfunction. We identified microglia and …
[HTML][HTML] Sepsis-associated encephalopathy: a vicious cycle of immunosuppression
C Ren, R Yao, H Zhang, Y Feng, Y Yao - Journal of neuroinflammation, 2020 - Springer
Sepsis-associated encephalopathy (SAE) is commonly complicated by septic conditions,
and is responsible for increased mortality and poor outcomes in septic patients …
and is responsible for increased mortality and poor outcomes in septic patients …
[HTML][HTML] What SARS-CoV-2 does to our brains
T Aschman, R Mothes, FL Heppner, H Radbruch - Immunity, 2022 - cell.com
Neurological symptoms in SARS-CoV-2-infected patients have been reported, but their
cause remains unclear. In theory, the neurological symptoms observed after SARS-CoV-2 …
cause remains unclear. In theory, the neurological symptoms observed after SARS-CoV-2 …