Formulation approaches to pediatric oral drug delivery: benefits and limitations of current platforms
Introduction: Most conventional drug delivery systems are not acceptable for pediatric
patients as they differ in their developmental status and dosing requirements from other …
patients as they differ in their developmental status and dosing requirements from other …
Additive manufacturing with 3D printing: progress from bench to bedside
Abstract Three-dimensional (3D) printing was discovered in the 1980s, and many industries
have embraced it, but the pharmaceutical industry is slow or reluctant to adopt it. Spiritam® …
have embraced it, but the pharmaceutical industry is slow or reluctant to adopt it. Spiritam® …
Application of 3D printing technology and quality by design approach for development of age-appropriate pediatric formulation of baclofen
Pediatric population is a sensitive sector of the healthcare and pharmaceutical field with
additional needs compared to the adult population. Extemporaneous formulations for …
additional needs compared to the adult population. Extemporaneous formulations for …
Off-label use of medicines in neonates, infants, children, and adolescents: a joint policy statement by the European Academy of Paediatrics and the European society …
L Schrier, A Hadjipanayis, T Stiris… - European journal of …, 2020 - Springer
Health-care professionals who prescribe medicines have the professional duty to choose
medicines that are in the best interest of their individual patient, irrespective if that patient is …
medicines that are in the best interest of their individual patient, irrespective if that patient is …
Direct powder extrusion 3d printing of praziquantel to overcome neglected disease formulation challenges in paediatric populations
For the last 40 years, praziquantel has been the standard treatment for schistosomiasis, a
neglected parasitic disease affecting more than 250 million people worldwide. However …
neglected parasitic disease affecting more than 250 million people worldwide. However …
Orally disintegrating tablets and orally disintegrating mini tablets–novel dosage forms for pediatric use
T Comoglu, E Dilek Ozyilmaz - Pharmaceutical Development and …, 2019 - Taylor & Francis
The oral administration route is considered to be the most widely used route because of its
convenience of administration and manufacturing. Dosage forms, like orally disintegrating …
convenience of administration and manufacturing. Dosage forms, like orally disintegrating …
An update of pharmacological management in children with functional constipation
A de Geus, IJN Koppen, RB Flint, MA Benninga… - Pediatric Drugs, 2023 - Springer
Functional constipation is a common problem in childhood worldwide and has a great
impact on social, physical, and emotional functioning of affected children and their …
impact on social, physical, and emotional functioning of affected children and their …
Preventing home medication administration errors
Medication administration errors that take place in the home are common, especially when
liquid preparations are used and complex medication schedules with multiple medications …
liquid preparations are used and complex medication schedules with multiple medications …
Acceptability of uncoated mini-tablets in neonates—a randomized controlled trial
V Klingmann, A Seitz, T Meissner, J Breitkreutz… - The Journal of …, 2015 - Elsevier
Objective To evaluate the suitability of drug-free solid dosage forms (2 mm mini-tablets) as
an alternative administration modality in neonates in comparison with syrup. Study design A …
an alternative administration modality in neonates in comparison with syrup. Study design A …
Pediatric oral formulations: an updated review of commercially available pediatric oral formulations since 2007
RG Strickley - Journal of Pharmaceutical Sciences, 2019 - Elsevier
Oral pediatric formulations are either ready-to-use or require manipulation and multiuse or
single-use. Strong encouragement for preservative-free pediatric formulations has resulted …
single-use. Strong encouragement for preservative-free pediatric formulations has resulted …