Clinical and experimental insight into pathophysiology, comorbidity and therapy of absence seizures
Absence seizures in children and teenagers are generally considered relatively benign
because of their non-convulsive nature and the large incidence of remittance in early …
because of their non-convulsive nature and the large incidence of remittance in early …
Dynamics of networks during absence seizure's on-and offset in rodents and man
A Lüttjohann, G van Luijtelaar - Frontiers in physiology, 2015 - frontiersin.org
Network mechanisms relevant for the generation, maintenance and termination of spike-
wave discharges (SWD), the neurophysiological hallmark of absence epilepsy, are still …
wave discharges (SWD), the neurophysiological hallmark of absence epilepsy, are still …
Enhanced tonic GABAA inhibition in typical absence epilepsy
DW Cope, G Di Giovanni, SJ Fyson, G Orbán… - Nature medicine, 2009 - nature.com
The cellular mechanisms underlying typical absence seizures, which characterize various
idiopathic generalized epilepsies, are not fully understood, but impaired γ-aminobutyric acid …
idiopathic generalized epilepsies, are not fully understood, but impaired γ-aminobutyric acid …
T-type calcium channel blockers that attenuate thalamic burst firing and suppress absence seizures
E Tringham, KL Powell, SM Cain, K Kuplast… - Science translational …, 2012 - science.org
Absence seizures are a common seizure type in children with genetic generalized epilepsy
and are characterized by a temporary loss of awareness, arrest of physical activity, and …
and are characterized by a temporary loss of awareness, arrest of physical activity, and …
Absence seizure control by a brain computer interface
VA Maksimenko, S Van Heukelum, VV Makarov… - Scientific Reports, 2017 - nature.com
The ultimate goal of epileptology is the complete abolishment of epileptic seizures. This
might be achieved by a system that predicts seizure onset combined with a system that …
might be achieved by a system that predicts seizure onset combined with a system that …
Bidirectional control of generalized epilepsy networks via rapid real-time switching of firing mode
JM Sorokin, TJ Davidson, E Frechette, AM Abramian… - Neuron, 2017 - cell.com
Thalamic relay neurons have well-characterized dual firing modes: bursting and tonic
spiking. Studies in brain slices have led to a model in which rhythmic synchronized spiking …
spiking. Studies in brain slices have led to a model in which rhythmic synchronized spiking …
Sleep spindles and spike–wave discharges in EEG: their generic features, similarities and distinctions disclosed with Fourier transform and continuous wavelet …
E Sitnikova, AE Hramov, AA Koronovsky… - Journal of neuroscience …, 2009 - Elsevier
Epileptic activity in the form of spike–wave discharges (SWD) appears in the
electroencephalogram (EEG) during absence seizures. A relationship between SWD and …
electroencephalogram (EEG) during absence seizures. A relationship between SWD and …
Inherited cortical HCN1 channel loss amplifies dendritic calcium electrogenesis and burst firing in a rat absence epilepsy model
MHP Kole, AU Bräuer, GJ Stuart - The Journal of physiology, 2007 - Wiley Online Library
While idiopathic generalized epilepsies are thought to evolve from temporal highly
synchronized oscillations between thalamic and cortical networks, their cellular basis …
synchronized oscillations between thalamic and cortical networks, their cellular basis …
Genetic enhancement of thalamocortical network activity by elevating α1G-mediated low-voltage-activated calcium current induces pure absence epilepsy
WL Ernst, Y Zhang, JW Yoo, SJ Ernst… - Journal of …, 2009 - Soc Neuroscience
Absence seizures are a leading form of childhood epilepsy. Human and mouse P/Q-type
calcium channel gene mutations initiate a complex absence epilepsy and ataxia phenotype …
calcium channel gene mutations initiate a complex absence epilepsy and ataxia phenotype …
Pathologic electrographic changes after experimental traumatic brain injury
Objective To investigate possible electroencephalography (EEG) correlates of
epileptogenesis after traumatic brain injury (TBI) using the fluid percussion model. Methods …
epileptogenesis after traumatic brain injury (TBI) using the fluid percussion model. Methods …