[HTML][HTML] Epidemiology of tularemia

Ş Gürcan - Balkan medical journal, 2014 - dergipark.org.tr
Tularemia is considered to have existed in Anatolia for several thousand years. There are
suspicions regarding its use in biological warfare in the Neshite-Arzawan conflict. The …

[HTML][HTML] Immunity to Francisella

SC Cowley, KL Elkins - Frontiers in microbiology, 2011 - frontiersin.org
In recent years, studies on the intracellular pathogen Francisella tularensis have greatly
intensified, generating a wealth of new information on the interaction of this organism with …

A Mutant of Francisella tularensis Strain SCHU S4 Lacking the Ability To Express a 58-Kilodalton Protein Is Attenuated for Virulence and Is an Effective Live Vaccine

S Twine, M Byström, W Chen, M Forsman… - Infection and …, 2005 - Am Soc Microbiol
Francisella tularensis subsp. tularensis (type A) strain SCHU S4 is a prototypic strain of the
pathogen that is highly virulent for humans and other mammals. Its intradermal (id) 50 …

Toll-Like Receptor 2 Is Required for Inflammatory Responses to Francisella tularensis LVS

J Katz, P Zhang, M Martin, SN Vogel… - Infection and …, 2006 - Am Soc Microbiol
Francisella tularensis, a gram-negative bacterium, is the etiologic agent of tularemia and has
recently been classified as a category A bioterrorism agent. Infections with F. tularensis …

Prophylactic and therapeutic use of antibodies for protection against respiratory infection with Francisella tularensis

GS Kirimanjeswara, JM Golden, CS Bakshi… - The Journal of …, 2007 - journals.aai.org
The role of Abs in protection against respiratory infection with the intracellular bacterium
Francisella tularensis is not clear. To investigate the ability of Abs to clear bacteria from the …

The Immunologically Distinct O Antigens from Francisella tularensis Subspecies tularensis and Francisella novicida Are both Virulence Determinants and Protective …

RM Thomas, RW Titball, PCF Oyston… - Infection and …, 2007 - Am Soc Microbiol
We have determined the sequence of the gene cluster encoding the O antigen in Francisella
novicida and compared it to the previously reported O-antigen cluster in Francisella …

Vaccines Against Francisella Tularensis

J Wayne Conlan, PCF Oyston - … of the New York Academy of …, 2007 - Wiley Online Library
Francisella tularensis is one of the most pathogenic pathogens known, especially when
disseminated as a small particle aerosol. Because of this, it was developed into a biological …

Aerosol-, but not intradermal-immunization with the live vaccine strain of Francisella tularensis protects mice against subsequent aerosol challenge with a highly …

JW Conlan, H Shen, R KuoLee, X Zhao, W Chen - Vaccine, 2005 - Elsevier
Francisella tularensis is an extremely virulent facultative intracellular bacterial pathogen of
many mammalian species including mice and humans in which it causes a spectrum of …

Intranasal Vaccination Induces Protective Immunity against Intranasal Infection with Virulent Francisella tularensis Biovar A

TH Wu, JA Hutt, KA Garrison, LS Berliba… - Infection and …, 2005 - Am Soc Microbiol
The inhalation of Francisella tularensis biovar A causes pneumonic tularemia associated
with high morbidity and mortality rates in humans. Exposure to F. tularensis usually occurs …

AcpA Is a Francisella Acid Phosphatase That Affects Intramacrophage Survival and Virulence

NP Mohapatra, A Balagopal, S Soni… - Infection and …, 2007 - Am Soc Microbiol
AcpA of Francisella spp. is a respiratory-burst-inhibiting acid phosphatase that also exhibits
phospholipase C activity. To better understand the molecular basis of AcpA in virulence, a …