Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in
the elderly population in the Western world. AMD is a clinically heterogeneous disease …

Late-onset retinal degeneration (L-ORD) is a type of retinal dystrophy marked by nyctalopia
and subretinal pigment epithelium deposits, which eventually promote retinal atrophy with …

Purpose To study choriocapillaris blood flow in age-related macular degeneration (AMD)
using optical coherence tomography angiography (OCTA) and study its correlation to visual …

Previous models of disease in age-related macular degeneration (AMD) were incomplete in
that they did not encompass subretinal drusenoid deposits (pseudodrusen), subtypes of …

Purpose: To characterize longitudinal structural changes in early stages of late-onset retinal
degeneration to investigate pathogenic mechanisms. Methods: Two affected siblings, both …

The gene that encodes C1q/TNF-related protein 5 (CTRP5), a secreted protein of the C1q
family, is mutated in individuals with late-onset retinal degeneration. CTRP5 is widely …

Background: Late-onset retinal degeneration (L-ORD) is a rare autosomal dominant retinal
dystrophy related to C1QTNF5 gene variants. Materials and methods: Twenty-six patients …

Purpose: To describe in detail the phenotype of a patient with Bietti crystalline dystrophy
(BCD) complicated by choroidal neovascularization (CNV) and the response to intravitreal …

Inherited retinal dystrophies encompass a diverse group of disorders affecting the structure
and function of the retina, leading to progressive visual impairment and, in severe cases …

Purpose To characterize the association of reticular pseudodrusen (RPD) with late-onset
retinal degeneration (L-ORD) using multimodal imaging. Design Prospective, 2-center …