Platelets: at the nexus of antimicrobial defence

MR Yeaman - Nature Reviews Microbiology, 2014 - nature.com
Platelets have traditionally been viewed as fragmentary mediators of coagulation. However,
recent molecular and cellular evidence suggests that they have multiple roles in host …

Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes

Y Zhang, V Bharathi, T Dokoshi… - Proceedings of the …, 2024 - National Acad Sciences
It is unclear how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
leads to the strong but ineffective inflammatory response that characterizes severe …

Recent progress in drug targets and inhibitors towards combating leishmaniasis

S Vijayakumar, P Das - Acta tropica, 2018 - Elsevier
Lesihmaniasis is one of the major neglected tropical disease caused by the parasite of the
genus Leishmania. The disease has more than one clinical forms and the visceral form is …

Therapeutic potential of antimicrobial peptides against pathogenic protozoa

CL Hagemann, AJ Macedo, T Tasca - Parasitology Research, 2024 - Springer
Protozoal infections cause significant morbidity and mortality in humans and animals. The
use of several antiprotozoal drugs is associated with serious adverse effects and resistance …

[HTML][HTML] Peptides to tackle leishmaniasis: Current status and future directions

AA Robles-Loaiza, EA Pinos-Tamayo… - International journal of …, 2021 - mdpi.com
Peptide-based drugs are an attractive class of therapeutic agents, recently recognized by
the pharmaceutical industry. These molecules are currently being used in the development …

[HTML][HTML] MM-GBSA and QM/MM simulation-based in silico approaches for the inhibition of Acinetobacter baumannii class D OXA-24 β-lactamase using antimicrobial …

M Mandal, S Mandal - Chemical Physics Impact, 2024 - Elsevier
The antimicrobial peptides (AMPs) have been regarded as the next generation antibiotics.
This study aimed to explore the AMP inhibitors of β-lactamase enzyme employing …

[HTML][HTML] Antimicrobial activity of RP-1 peptide conjugate with ferrocene group

NCS Costa, JP Piccoli, NA Santos-Filho… - Plos one, 2020 - journals.plos.org
Parasitic diseases are a neglected and serious problem, especially in underdeveloped
countries. Among the major parasitic diseases, Leishmaniasis figures as an urgent …

Antiparasitic peptides

J Pretzel, F Mohring, S Rahlfs, K Becker - Yellow Biotechnology I: Insect …, 2013 - Springer
<? xm-replace_text {Heading}?> Abstract The most important parasitic diseases, malaria,
leishmaniasis, trypanosomiasis, and schistosomiasis, are a great burden to mankind …

Immunotherapy in clinical canine leishmaniosis: a comparative update

M Baxarias, P Martínez-Orellana, G Baneth… - Research in veterinary …, 2019 - Elsevier
Leishmaniosis due to Leishmania infantum is a complex infection that can affect both
humans and dogs, and present a wide range of clinical signs and clinicopathological …

Realistic and critical review of the state of systemic anti-microbial peptides

G Wang, AF Mechesso - ADMET and DMPK, 2022 - hrcak.srce.hr
Sažetak Antimicrobial peptide research remains active not only because of the growing
antibiotic resistance problem but also our desire to understand the role of innate immune …