Protective effects of diets rich in polyphenols in cigarette smoke (CS)-induced oxidative damages and associated health implications

M Rudrapal, S Maji, SK Prajapati, P Kesharwani… - Antioxidants, 2022 - mdpi.com
Cigarette smoking has been responsible for causing many life-threatening diseases such as
pulmonary and cardiovascular diseases as well as lung cancer. One of the prominent health …

A narrative review on potential applications of spanlastics for nose-to-brain delivery of therapeutically active agents

N Nadim, AA Khan, S Khan, R Parveen, J Ali - Advances in Colloid and …, 2024 - Elsevier
Spanlastics, which are commonly referred to as elastic niosomes, presents a modified
advancement in the area of colloidal system based drug delivery carriers. They are different …

Spanlastic nanovesicles for enhanced ocular delivery of vanillic acid: design, in vitro characterization, and in vivo anti-inflammatory evaluation

SS Ibrahim, H Abd-Allah - International Journal of Pharmaceutics, 2022 - Elsevier
Spanlastics are novel surfactant-based, elastic vesicular nanocarriers composed of spans
and edge activators. The present work aims to exploit their special penetration enhancing …

Spanlastics as an efficient delivery system for the enhancement of thymoquinone anticancer efficacy: Fabrication and cytotoxic studies against breast cancer cell lines

E Alaaeldin, M Mostafa, HF Mansour… - Journal of Drug Delivery …, 2021 - Elsevier
Thymoquinone (TQ), a pleiotropic compound isolated from the seeds of Nigella sativa has a
great potential as a chemotherapeutic agent against several cancers. However, its limited …

Glycerospanlastics: State-of-the-art two-in-one nano-vesicles for boosting ear drug delivery in otitis media treatment

M Magdy, E Elmowafy, M Elassal, RAH Ishak - International Journal of …, 2023 - Elsevier
The purpose of this research was to design innovative nanovesicles for ototopical
conveyance of triamcinolone acetonide (TA) for otitis media (OM) treatment via incorporating …

Formulation and characterization of quercetin-loaded Prunus armeniaca gum nanoparticles with enhanced anti-bacterial effect

EA Mazyed, G Magdy, E Elekhnawy… - Journal of Drug Delivery …, 2024 - Elsevier
Owing to the dissemination of antibiotic resistance among Staphylococcus aureus bacteria,
it is critical to find out new, safe, and effective alternatives. Plants are a major source of many …

Formulation-by-design of efinaconazole spanlastic nanovesicles for transungual delivery using statistical risk management and multivariate analytical techniques

RM Almuqbil, N Sreeharsha, AB Nair - Pharmaceutics, 2022 - mdpi.com
As regulatory and technical landscapes for pharmaceutical formulation development are
rapidly evolving, a risk-management approach using multivariate analysis is highly essential …

Fabrication and optimization of raloxifene loaded spanlastics vesicle for transdermal delivery

MD Ansari, P Solanki, J Pandit, RN Jahan… - Journal of Drug Delivery …, 2022 - Elsevier
This research work is envisioned for the development and optimization of Raloxifene HCL
loaded spanlastics. Raloxifene HCL, a selective estrogen receptor modulator (SERM), is …

Formulation and optimization of folate-bovine serum albumin-coated ethoniosomes of pterostilbene as a targeted drug delivery system for lung cancer: In vitro and in …

NAN Hanafy, RH Abdelbadea, AE Abdelaziz… - Cancer …, 2023 - Springer
This study aimed to overcome the poor solubility of pterostilbene (PTS) by developing
promising reconstituted proethoniosomes (PENs). The reconstituted PENs loaded with PTS …

Clove oil endorsed transdermal flux of dronedarone hydrochloride loaded bilosomal nanogel: Factorial design, in vitro evaluation and ex vivo permeation

MH Teaima, JM Alsofany, MA El-Nabarawi - AAPS PharmSciTech, 2022 - Springer
The goal of this study was to develop a bilosomal gel formulation to enhance transdermal
permeability of dronedarone hyrdrochloride (DRN) which suffers from poor oral absorption …