Tumor‐microenvironment‐responsive nanomedicine for enhanced cancer immunotherapy
The past decades have witnessed great progress in cancer immunotherapy, which has
profoundly revolutionized oncology, whereas low patient response rates and potential …
profoundly revolutionized oncology, whereas low patient response rates and potential …
[HTML][HTML] Peptide-based nanomaterials: Self-assembly, properties and applications
Peptide-based materials that have diverse structures and functionalities are an important
type of biomaterials. In former times, peptide-based nanomaterials with excellent stability …
type of biomaterials. In former times, peptide-based nanomaterials with excellent stability …
Immune checkpoint therapy for solid tumours: clinical dilemmas and future trends
Q Sun, Z Hong, C Zhang, L Wang, Z Han… - Signal transduction and …, 2023 - nature.com
Abstract Immune-checkpoint inhibitors (ICBs), in addition to targeting CTLA-4, PD-1, and PD-
L1, novel targeting LAG-3 drugs have also been approved in clinical application. With the …
L1, novel targeting LAG-3 drugs have also been approved in clinical application. With the …
Multifunctional metal-organic framework-based nanoreactor for starvation/oxidation improved indoleamine 2, 3-dioxygenase-blockade tumor immunotherapy
L Dai, M Yao, Z Fu, X Li, X Zheng, S Meng… - Nature …, 2022 - nature.com
Inhibited immune response and low levels of delivery restrict starvation cancer therapy
efficacy. Here, we report on the co-delivery of glucose oxidase (GOx) and indoleamine 2, 3 …
efficacy. Here, we report on the co-delivery of glucose oxidase (GOx) and indoleamine 2, 3 …
Improving cancer immunotherapy using nanomedicines: progress, opportunities and challenges
Multiple nanotherapeutics have been approved for patients with cancer, but their effects on
survival have been modest and, in some examples, less than those of other approved …
survival have been modest and, in some examples, less than those of other approved …
Second near‐infrared photothermal semiconducting polymer nanoadjuvant for enhanced cancer immunotherapy
Immunotherapy has offered new treatment options for cancer; however, the therapeutic
benefits are often modest and desired to be improved. A semiconducting polymer …
benefits are often modest and desired to be improved. A semiconducting polymer …
Molecularly stimuli-responsive self-assembled peptide nanoparticles for targeted imaging and therapy
Y Zhou, Q Li, Y Wu, X Li, Y Zhou, Z Wang, H Liang… - ACS …, 2023 - ACS Publications
Self-assembly has emerged as an extensively used method for constructing biomaterials
with sizes ranging from nanometers to micrometers. Peptides have been extensively …
with sizes ranging from nanometers to micrometers. Peptides have been extensively …
Tumor microenvironment‐activatable prodrug vesicles for nanoenabled cancer chemoimmunotherapy combining immunogenic cell death induction and CD47 …
F Zhou, B Feng, H Yu, D Wang, T Wang… - Advanced …, 2019 - Wiley Online Library
Chemoimmunotherapy is reported to activate a robust T cell antitumor immune response by
triggering immunogenic cell death (ICD), which has initiated a number of clinical trials …
triggering immunogenic cell death (ICD), which has initiated a number of clinical trials …
Semiconducting polymer nanoparticles with surface‐mimicking protein secondary structure as lysosome‐targeting chimaeras for self‐synergistic cancer …
Immunotherapy has received tremendous attention for tumor treatment, but the efficacy is
greatly hindered by insufficient tumor‐infiltration of immune cells and immunosuppressive …
greatly hindered by insufficient tumor‐infiltration of immune cells and immunosuppressive …
Precise nanomedicine for intelligent therapy of cancer
Precise nanomedicine has been extensively explored for efficient cancer imaging and
targeted cancer therapy, as evidenced by a few breakthroughs in their preclinical and …
targeted cancer therapy, as evidenced by a few breakthroughs in their preclinical and …