Abstract Phosphatidylinositol (4, 5) bisphosphate (PI (4, 5) P2) has become a major focus in
biochemistry, cell biology and physiology owing to its diverse functions at the plasma …

Elizabethkingia spp. is a ubiquitous pathogenic bacterium that has been identified as the
causal agent for a variety of conditions such as meningitis, pneumonia, necrotizing fasciitis …

Abstract Phosphoinositide-specific phospholipase Cs (PLCs) are expressed in all
mammalian cells and play critical roles in signal transduction. To obtain a comprehensive …

Phosphatidylinositol (PI) is an essential structural component of eukaryotic membranes that
also serves as the common precursor for polyphosphoinositide (PPIn) lipids. Despite the …

Cation− π interactions play an important role in biomolecular recognition, including
interactions between membrane phosphatidylcholine lipids and aromatic amino acids of …

Macrocyclic peptides show promise in targeting high-value therapeutically relevant binding
sites due to their high affinity and specificity. However, their clinical application is often …

Peripheral membrane proteins (PMPs) include a wide variety of proteins that have in
common to bind transiently to the chemically complex interfacial region of membranes …

Cytochrome c nitrite reductase (NrfA) catalyzes the reduction of nitrite to ammonium in the
dissimilatory nitrate reduction to ammonium (DNRA) pathway, a process that competes with …

Membrane-binding interfaces of peripheral proteins are restricted to a small part of their
exposed surface, so the ability to engage in strong selective interactions with membrane …

Abstract Phospholipase A2 (PLA2) exerts a wide range of biological effects and attracts a lot
of attention of researchers. Two sites are involved in manifestation of PLA2 enzymatic …