DNA methylation is the most well studied of the epigenetic regulators in relation to
environmental exposures. To date, numerous studies have detailed the manner by which …

The increasing prevalence of neurodevelopmental disorders, especially autism spectrum
disorders (ASD) and attention deficit hyperactivity disorder (ADHD), calls for more research …

Current evidence supports the notion that environmental exposures are associated with
DNA-methylation and expression changes that can impact human health. Our objective was …

Importance Persistent environmental pollutants may represent a modifiable risk factor
involved in the gene-time-environment hypothesis in amyotrophic lateral sclerosis (ALS) …

There is now compelling evidence that gene by environment interactions are important in
the etiology of autism spectrum disorders (ASDs). However, the mechanisms by which …

Genetic studies traditionally focus on DNA as the molecule that passes information on from
parents to their offspring. Changes in the DNA code alter heritable information and can more …

Parkinson's disease (PD) is the second most common neurodegenerative disorder with an
unclear etiology and no disease-modifying treatment to date. PD is considered a …

Microplastics (MPs) pollution is a newly emerging environmental issue. MPs can accumulate
within animals and humans, which can pose a serious health threat. Petroleum-based …

Background: Pesticide exposure is associated with many long-term health outcomes; the
potential underlying mechanisms are not well established for most associations. Epigenetic …

The acquisition of reproductive competence is organized and activated by steroid hormones
acting upon the hypothalamus during critical windows of development. This review …