The age-related dysregulation and decline of the immune system—collectively termed
“immunosenescence”—has been generally associated with an increased susceptibility to …

Immunosenescence is a series of age-related changes that affect the immune system and,
with time, lead to increased vulnerability to infectious diseases. This Review addresses …

These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

In the older adult, the benefits of vaccination to prevent infectious disease are limited, mainly
because of the adaptive immune system's inability to generate protective immunity. The age …

The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

Coinfections involving viruses are being recognized to influence the disease pattern that
occurs relative to that with single infection. Classically, we usually think of a clinical …

Aging is associated with a dysregulation of the immune response, loosely termed
“immunosenescence.” Each part of the immune system is influenced to some extent by the …

The impact of intrinsic aging upon human peripheral blood T cell subsets remains
incompletely quantified and understood. This impact must be distinguished from the …

Humans are infected with a variety of acute and chronic pathogens over the course of their
lives, and pathogen-driven selection has shaped the immune system of humans. The same …

Immune responses differ between laboratory mice and humans. Chronic infection with
viruses and parasites are common in humans, but are absent in laboratory mice, and thus …