Mechanisms of AMPK in the maintenance of ATP balance during energy metabolism

R Ke, Q Xu, C Li, L Luo, D Huang - Cell Biology International, 2018 - Wiley Online Library
AMP‐activated protein kinase (AMPK) is a conserved sensor of cellular energy change and
is activated by increased AMP/ATP and/or ADP/ATP ratios. AMPK maintains the energy …

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

JD Hayes, AT Dinkova-Kostova - Trends in biochemical sciences, 2014 - cell.com
Nuclear factor-erythroid 2 p45-related factor 2 (Nrf2, also called Nfe2l2) is a transcription
factor that regulates the cellular redox status. Nrf2 is controlled through a complex …

The impact of moderate-intensity continuous or high-intensity interval training on adipogenesis and browning of subcutaneous adipose tissue in obese male rats

M Khalafi, H Mohebbi, ME Symonds, P Karimi, A Akbari… - Nutrients, 2020 - mdpi.com
This study compares the effect of two types of exercise training, ie, moderate-intensity
continuous training (MICT) or high-intensity interval training (HIIT) on the browning of …

Interactions between insulin and exercise

EA Richter, L Sylow, M Hargreaves - Biochemical journal, 2021 - portlandpress.com
The interaction between insulin and exercise is an example of balancing and modifying the
effects of two opposing metabolic regulatory forces under varying conditions. While insulin is …

Molecular regulation of fatty acid oxidation in skeletal muscle during aerobic exercise

AM Lundsgaard, AM Fritzen, B Kiens - Trends in Endocrinology & …, 2018 - cell.com
This review summarizes how fatty acid (FA) oxidation is regulated in skeletal muscle during
exercise. From the available evidence it seems that acetyl-CoA availability in the …

Muscle lipid metabolism: role of lipid droplets and perilipins

PE Morales, JL Bucarey… - Journal of diabetes …, 2017 - Wiley Online Library
Skeletal muscle is one of the main regulators of carbohydrate and lipid metabolism in our
organism, and therefore, it is highly susceptible to changes in glucose and fatty acid (FA) …

Regulation of substrate oxidation preferences in muscle by the peptide hormone adropin

S Gao, RP McMillan, J Jacas, Q Zhu, X Li, GK Kumar… - Diabetes, 2014 - Am Diabetes Assoc
Rigorous control of substrate oxidation by humoral factors is essential for maintaining
metabolic homeostasis. During feeding and fasting cycles, carbohydrates and fatty acids are …

Exercise metabolism: fuels for the fire

M Hargreaves, LL Spriet - Cold Spring …, 2018 - perspectivesinmedicine.cshlp.org
During exercise, the supply of adenosine triphosphate (ATP) is essential for the energy-
dependent processes that underpin ongoing contractile activity. These pathways involve …

Targeting CD36 as biomarker for metastasis prognostic: how far from translation into clinical practice?

AM Enciu, E Radu, ID Popescu… - BioMed research …, 2018 - Wiley Online Library
Metastasis requires cellular changes related to cell‐to‐cell and cell‐to‐matrix adhesion,
immune surveillance, activation of growth and survival signalling pathways, and epigenetic …

CD36 actions in the heart: lipids, calcium, inflammation, repair and more?

NA Abumrad, IJ Goldberg - Biochimica et Biophysica Acta (BBA)-Molecular …, 2016 - Elsevier
CD36 is a multifunctional immuno-metabolic receptor with many ligands. One of its
physiological functions in the heart is the high-affinity uptake of long-chain fatty acids (FAs) …