Acidocalcisomes

R Docampo, SNJ Moreno - Cell calcium, 2011 - Elsevier
Acidocalcisomes are acidic organelles containing calcium and a high concentration of
phosphorus in the form of pyrophosphate (PPi) and polyphosphate (poly P). Organelles with …

Evolution of acidocalcisomes and their role in polyphosphate storage and osmoregulation in eukaryotic microbes

R Docampo, P Ulrich… - … Transactions of the …, 2010 - royalsocietypublishing.org
Acidocalcisomes are acidic electron-dense organelles, rich in polyphosphate (poly P)
complexed with calcium and other cations. While its matrix contains enzymes related to poly …

Proteomic analysis of the acidocalcisome, an organelle conserved from bacteria to human cells

G Huang, PN Ulrich, M Storey, D Johnson… - PLoS …, 2014 - journals.plos.org
Acidocalcisomes are acidic organelles present in a diverse range of organisms from
bacteria to human cells. In this study acidocalcisomes were purified from the model …

The Role of Acidocalcisomes in Parasitic Protists1

SNJ Moreno, R Docampo - Journal of Eukaryotic Microbiology, 2009 - Wiley Online Library
Acidocalcisomes are acidic organelles with a high concentration of phosphorus present as
pyrophosphate (PPi) and polyphosphate (poly P) complexed with calcium and other cations …

Inorganic phosphate as an important regulator of phosphatases

CF Dick, ALA Dos-Santos… - Enzyme …, 2011 - Wiley Online Library
Cellular metabolism depends on the appropriate concentration of intracellular inorganic
phosphate (Pi). Pi starvation‐responsive genes appear to be involved in multiple metabolic …

New insights into roles of acidocalcisomes and contractile vacuole complex in osmoregulation in protists

R Docampo, V Jimenez, N Lander, ZH Li… - International review of cell …, 2013 - Elsevier
While free-living protists are usually subjected to hyposmotic environments, parasitic protists
are also in contact with hyperosmotic habitats. Recent work in one of these parasites …

Identification and characterization of an ectophosphatase activity involved in Acanthamoeba castellanii adhesion to host cells

LF Carvalho-Kelly, AL Freitas-Mesquita… - European Journal of …, 2023 - Elsevier
Acanthamoeba castellanii is a free-living amoeba and an opportunistic pathogen for
humans that can cause encephalitis and, more commonly, Acanthamoeba keratitis. During …

Euglena gracilis: Biochemical properties of a membrane bound ecto-phosphatase activity modulated by fluoroaluminate complexes and different trophic conditions

AL Freitas-Mesquita, LF Carvalho-Kelly… - European Journal of …, 2023 - Elsevier
The ecto-phosphatases belong to a group of enzymes closely associated with the cell
surface that has its catalytic site facing the extracellular environment, where different …

Interactions of trypanosomatids and triatomines

GA Schaub - Advances in insect physiology, 2009 - Elsevier
The intestinal tract of triatomines is colonized not only by Trypanosoma cruzi, the etiologic
agent of Chagas disease, but also by the insect flagellate Blastocrithidia triatomae, the rat …

Genomic comparison of Trypanosoma conorhini and Trypanosoma rangeli to Trypanosoma cruzi strains of high and low virulence

KR Bradwell, VN Koparde, AV Matveyev, MG Serrano… - BMC genomics, 2018 - Springer
Abstract Background Trypanosoma conorhini and Trypanosoma rangeli, like Trypanosoma
cruzi, are kinetoplastid protist parasites of mammals displaying divergent hosts, geographic …