An update on the clinical consequences of polypharmacy in older adults: a narrative review

JW Wastesson, L Morin, ECK Tan… - Expert opinion on drug …, 2018 - Taylor & Francis
Introduction: Polypharmacy, the use of multiple medications by one individual, is
increasingly common among older adults. Caring for the growing number of older people …

Polypharmacy: evaluating risks and deprescribing

AD Halli-Tierney, C Scarbrough, D Carroll - American family physician, 2019 - aafp.org
Polypharmacy, defined as regular use of at least five medications, is common in older adults
and younger at-risk populations and increases the risk of adverse medical outcomes. There …

Deprescribing: a narrative review of the evidence and practical recommendations for recognizing opportunities and taking action

E Reeve, W Thompson, B Farrell - European journal of internal medicine, 2017 - Elsevier
Deprescribing can be defined as the process of withdrawal or dose reduction of medications
which are considered inappropriate in an individual. The aim of this narrative review is to …

Potentially inappropriate prescribing in community-dwelling older people across Europe: a systematic literature review

E Tommelein, E Mehuys, M Petrovic, A Somers… - European journal of …, 2015 - Springer
Background Potentially inappropriate prescribing (PIP) is one of the main risk factors for
adverse drug events (ADEs) in older people. Purpose This systematic literature review aims …

Medication therapy management interventions in outpatient settings: a systematic review and meta-analysis

M Viswanathan, LC Kahwati, CE Golin… - JAMA internal …, 2015 - jamanetwork.com
Importance Medication therapy management (MTM) services (also calledclinical pharmacy
services) aim to reduce medication-related problems and their downstream outcomes …

Polypharmacy management in the older adults: a scoping review of available interventions

M Kurczewska-Michalak, P Lewek… - Frontiers in …, 2021 - frontiersin.org
Background: Polypharmacy paves the way for non-adherence, adverse drug reactions,
negative health outcomes, increased use of healthcare services and rising costs. Since it is …

Methods to reduce prescribing errors in elderly patients with multimorbidity

AH Lavan, PF Gallagher… - Clinical interventions in …, 2016 - Taylor & Francis
The global population of multimorbid older people is growing steadily. Multimorbidity is the
principal cause of complex polypharmacy, which in turn is the prime risk factor for …

Multi-morbidity and polypharmacy in older people: challenges and opportunities for clinical practice

P Aggarwal, SJ Woolford, HP Patel - Geriatrics, 2020 - mdpi.com
Multi-morbidity and polypharmacy are common in older people and pose a challenge for
health and social care systems, especially in the context of global population ageing. They …

Associations of polypharmacy and inappropriate medications with adverse outcomes in older adults with cancer: a systematic review and meta‐analysis

MR Mohamed, E Ramsdale, KP Loh, A Arastu… - The …, 2020 - academic.oup.com
Background Polypharmacy (PP) and potentially inappropriate medications (PIM) are highly
prevalent in older adults with cancer. This study systematically reviews the associations of …

Polypharmacy and potentially inappropriate medication use in geriatric oncology

M Sharma, KP Loh, G Nightingale, SG Mohile… - Journal of geriatric …, 2016 - Elsevier
Polypharmacy is a highly prevalent problem in older persons, and is challenging to assess
and improve due to variations in definitions of the problem and the heterogeneous methods …