A low toxic CRM1 degrader: Synthesis and anti-proliferation on MGC803 and HGC27

HW Xu, S Jia, M Liu, X Li, X Meng, X Wu, L Yu… - European Journal of …, 2020 - Elsevier
Abstract Chromosome region maintenance 1 (CRM1) is the sole nuclear exporter of several
tumor suppressor, a growth regulatory protein as an attractive cancer drug target. In the …