[HTML][HTML] Properties and behavior of carbon nanomaterials when interfacing neuronal cells: How far have we come?
In the last two decades, an increasing amount of studies have investigated the use of
components based on carbon-(nano) materials in the engineering of neural interfaces, to …
components based on carbon-(nano) materials in the engineering of neural interfaces, to …
Role of Rad51 and DNA repair in cancer: A molecular perspective
The maintenance of genome integrity is essential for any organism survival and for the
inheritance of traits to offspring. To the purpose, cells have developed a complex DNA repair …
inheritance of traits to offspring. To the purpose, cells have developed a complex DNA repair …
Entrenching role of cell cycle checkpoints and autophagy for maintenance of genomic integrity
Genomic integrity of the cell is crucial for the successful transmission of genetic information
to the offspring and its survival. Persistent DNA damage induced by endogenous and …
to the offspring and its survival. Persistent DNA damage induced by endogenous and …
In vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation
Homologous recombination (HR) uses a homologous template to accurately repair DNA
double-strand breaks and stalled replication forks to maintain genome stability. During …
double-strand breaks and stalled replication forks to maintain genome stability. During …
TLK1-mediated RAD54 phosphorylation spatio-temporally regulates Homologous Recombination Repair
Environmental agents like ionizing radiation (IR) and chemotherapeutic drugs can cause
severe damage to the DNA, often in the form of double-strand breaks (DSBs). Remaining …
severe damage to the DNA, often in the form of double-strand breaks (DSBs). Remaining …
DNA double strand break repair pathways in response to different types of ionizing radiation
G van de Kamp, T Heemskerk, R Kanaar… - Frontiers in …, 2021 - frontiersin.org
The superior dose distribution of particle radiation compared to photon radiation makes it a
promising therapy for the treatment of tumors. However, the cellular responses to particle …
promising therapy for the treatment of tumors. However, the cellular responses to particle …
DNA damage response and repair in perspective: Aedes aegypti, Drosophila melanogaster and Homo sapiens
Background The maintenance of genomic integrity is the responsibility of a complex
network, denominated the DNA damage response (DDR), which controls the lesion …
network, denominated the DNA damage response (DDR), which controls the lesion …
Nanopore analysis as a tool for studying rapid holliday junction dynamics and analyte binding
Holliday junctions (HJs) are an important class of nucleic acid structure utilized in DNA
break repair processes. As such, these structures have great importance as therapeutic …
break repair processes. As such, these structures have great importance as therapeutic …
Untousling the Role of Tousled-like Kinase 1 in DNA Damage Repair
I Ghosh, A De Benedetti - International Journal of Molecular Sciences, 2023 - mdpi.com
DNA damage repair lies at the core of all cells' survival strategy, including the survival
strategy of cancerous cells. Therefore, targeting such repair mechanisms forms the major …
strategy of cancerous cells. Therefore, targeting such repair mechanisms forms the major …
A novel landscape of nuclear human CDK2 substrates revealed by in situ phosphorylation
Y Chi, JH Carter, J Swanger, AV Mazin, RL Moritz… - Science …, 2020 - science.org
Cyclin-dependent kinase 2 (CDK2) controls cell division and is central to oncogenic
signaling. We used an “in situ” approach to identify CDK2 substrates within nuclei isolated …
signaling. We used an “in situ” approach to identify CDK2 substrates within nuclei isolated …