Metabolic anomalies contribute to tissue dysfunction. Current metabolism research spans
from organelles to populations, and new technologies can accommodate investigation …

Metabolic adaptation to viral infections critically determines the course and manifestations of
disease. At the systemic level, a significant feature of viral infection and inflammation that …

Mitochondria are membrane-enclosed organelles with endosymbiotic origins, harboring
independent genomes and a unique biochemical reaction network. To perform their critical …

Strigolactones (SLs) are a class of plant hormones that regulate numerous processes of
growth and development. SL perception and signal activation involves interaction between F …

Motivation Cells respond to environments by regulating gene expression to exploit
resources optimally. Recent advances in technologies allow for measuring the abundances …

Viruses depend on cellular metabolic resources to supply the energy and biomolecular
building blocks necessary for their replication. Human cytomegalovirus (HCMV), a leading …

Pyruvate kinase (PK) activators have potential therapeutic applications in diseases such as
sickle cell anemia. In this study, N-Substituted sulfonamide derivatives of 1, 4 …

Simple Summary Three different murine glioma cell lines were modified to downregulate
expression of the murine LDH-A gene using shRNA knockdown (KD) and compared to …

The heart is the most metabolically active organ in the body, sustaining a continuous and
high flux of nutrient catabolism via oxidative phosphorylation. The nature and relative …

Metabolites have emerged as central regulators of biological function, but understanding
mechanisms of metabolite regulation has proven challenging. In 2021 we have seen …