BACKGROUND The idea that memory is stored as enduring changes in the brain dates
back at least to the time of Plato and Aristotle (circa 350 BCE), but its scientific articulation …

The dentate gyrus (DG) has a key role in hippocampal memory formation. Intriguingly, DG
lesions impair many, but not all, hippocampus-dependent mnemonic functions, indicating …

GABAergic inhibitory circuits play an essential role in coordinating various hippocampal
functions. Several decades of work dedicated to a thorough characterization of hippocampal …

Episodic memories initially require rapid synaptic plasticity within the hippocampus for their
formation and are gradually consolidated in neocortical networks for permanent storage …

Adult hippocampal neurogenesis has been implicated in cognitive processes, such as
pattern separation, and in the behavioural effects of stress and antidepressants. Young adult …

Episodic memory reflects the ability to recollect the temporal and spatial context of past
experiences. Episodic memories depend on the hippocampus but have been proposed to …

What happens to memories as days, weeks and years go by has long been a fundamental
question in neuroscience and psychology. For decades, researchers have attempted to …

Recent studies suggest that a shared neural ensemble may link distinct memories encoded
close in time,,,,,,,,,,,. According to the memory allocation hypothesis,, learning triggers a …

The ability to form precise, episodic memories develops with age, with young children only
able to form gist-like memories that lack precision. The cellular and molecular events in the …

Many attempts have been made to localize the physical trace of a memory, or engram, in the
brain. However, until recently, engrams have remained largely elusive. In this Review, we …