Radiotherapy is a cornerstone of both curative and palliative cancer care. However,
radiotherapy is severely limited by radiation-induced toxicities. If these toxicities could be …

Ultrahigh dose-rate radiotherapy (RT), or'FLASH'therapy, has gained significant momentum
following various in vivo studies published since 2014 which have demonstrated a reduction …

In their seminal paper from 2014, Fauvadon et al. coined the term FLASH irradiation to
describe ultra‐high‐dose rate irradiation with dose rates greater than 40 Gy/s, which results …

High dose-rate radiotherapy, known as FLASH, has been shown to increase the differential
response between healthy and tumour tissue. Moreover, Very High Energy Electrons …

Pluridirectional high-energy agile scanning electronic radiotherapy (PHASER) is next-
generation medical linac technology for ultra-rapid highly conformal image-guided radiation …

Ultrahigh dose rate, FLASH radiotherapy has emerged as one of the most promising
innovations over the past decade in the field of radiation oncology, with the potential to …

This article first gives the authors' perspectives on how the field of plasma-based
acceleration (PBA) developed and how the current experiments, theory, and simulations are …

Very high energy electron (VHEE) beams have been proposed as an alternative
radiotherapy modality to megavoltage photons; they penetrate deeply without significant …

Simple Summary This review provides some highlights in the current radio (chemo) therapy
strategy for head and neck squamous cell carcinoma (HNSCC). The aim is to lead to a better …

The FLASH effect designates normal tissue sparing at ultra-high dose rate (UHDR,> 40
Gy/s) compared to conventional dose rate (∼ 0.1 Gy/s) irradiation while maintaining tumour …