[HTML][HTML] Complement in secondary thrombotic microangiopathy

LMP Palma, M Sridharan, S Sethi - Kidney international reports, 2021 - Elsevier
Thrombotic microangiopathy (TMA) is a condition characterized by thrombocytopenia and
microangiopathic hemolytic anemia (MAHA) with varying degrees of organ damage in the …

Thrombotic microangiopathy in children

LMP Palma, MH Vaisbich-Guimarães, M Sridharan… - Pediatric …, 2022 - Springer
The syndrome of thrombotic microangiopathy (TMA) is a clinical-pathological entity
characterized by microangiopathic hemolytic anemia, thrombocytopenia, and end organ …

Hemolytic uremic syndrome in a developing country: consensus guidelines

A Bagga, P Khandelwal, K Mishra, R Thergaonkar… - Pediatric …, 2019 - Springer
Background Hemolytic uremic syndrome (HUS) is a leading cause of acute kidney injury in
children. Although international guidelines emphasize comprehensive evaluation and …

Clinical and immunological profile of anti-factor H antibody associated atypical hemolytic uremic syndrome: a nationwide database

M Puraswani, P Khandelwal, H Saini, S Saini… - Frontiers in …, 2019 - frontiersin.org
Background: Atypical hemolytic uremic syndrome (aHUS), an important cause of acute
kidney injury (AKI), is characterized by dysregulation of the alternative complement pathway …

Genetic testing in pediatric kidney disease

V Arora, K Anand, I Chander Verma - The Indian Journal of Pediatrics, 2020 - Springer
The advent of next gene sequencing technology has led to the publication of a profusion of
papers on monogenic contributions to pediatric kidney disorders. It started with the discovery …

Dysregulation of immune cell subpopulations in atypical hemolytic uremic syndrome

IR Chen, CC Huang, SJ Tu, GJ Wang, PC Lai… - International Journal of …, 2023 - mdpi.com
Atypical hemolytic uremic syndrome (aHUS) is a rare, life-threatening thrombotic
microangiopathy. Definitive biomarkers for disease diagnosis and activity remain elusive …

Atypical hemolytic uremic syndrome in Brazil: clinical presentation, genetic findings and outcomes of a case series in adults and children treated with eculizumab

LMP Palma, RG Eick, GC Dantas… - Clinical Kidney …, 2021 - academic.oup.com
Background Atypical hemolytic uremic syndrome (aHUS) is characterized by
microangiopathic hemolytic anemia, thrombocytopenia and kidney injury caused by a …

Anti-factor B antibodies in atypical hemolytic uremic syndrome

P Khandelwal, S Nambiar, R Saini, S Saini… - Pediatric …, 2024 - Springer
Background The etiology of atypical hemolytic uremic syndrome (aHUS) is unknown in 30–
40% of patients. Anti-factor B (FB) antibodies are reported in C3 glomerulopathy (C3G) and …

Copy number variation analysis using next-generation sequencing identifies the CFHR3/CFHR1 deletion in atypical hemolytic uremic syndrome: a case report

J Park, HY Yhim, KP Kang, TW Bae, YG Cho - Hematology, 2022 - Taylor & Francis
Objectives Atypical hemolytic uremic syndrome (aHUS) is characterized by a triad of
thrombocytopenia, microangiopathic hemolytic anemia, and acute renal failure resulting …

[HTML][HTML] Thrombotic Microangiopathy in children: Redefining HUS, TTP and related disorders!

M Manglani, P Kini - Pediatric Hematology Oncology Journal, 2024 - Elsevier
Thrombotic microangiopathy (TMA) is a triad of microangiopathic hemolytic anemia,
thrombocytopenia, and end-organ ischaemic damage. The primary mechanism involved is …