Laboratory investigations provide physicians with objective data to aid in disease diagnosis,
clinical decision making, and patient follow up. Clinical interpretation of laboratory test …

GFR is the best indicator of renal function in children and adolescents and is critical for
diagnosing acute and chronic kidney impairment, intervening early to prevent end-stage …

Using data (2655 observations from 928 participants) from the Chronic Kidney Disease in
Children Study, we developed and internally validated new glomerular filtration rate …

Human immunodeficiency virus (HIV) is now a confirmed risk factor for kidney disease with
higher burden in persons of African origin. The aim of this study is to assess the renal …

Background. We recently published and validated the new serum creatinine (Scr)-based full-
age-spectrum equation (FAScrea) for estimating the glomerular filtration rate (GFR) for …

Reference intervals (RIs) for common clinical laboratory tests are usually not developed
separately for different subpopulations. The aim of this study was to investigate racial/ethnic …

There is a clear sex–gender gap in the prevention and occurrence of diseases, and in the
outcomes and treatments, which is relevant to women in the majority of cases. Attitudes …

Background Chronic, high-level lead exposure is a known risk factor for kidney disease. The
effect of current low-level environmental lead exposure is less well known, particularly …

Results Mean±SD iGFR was 101±32 ml/min per 1.73 m 2. When evaluating agreement
between these formulas and iGFR (eg correlation, Bland Altman plots, bias, and accuracies) …

Background Most validations of paediatric glomerular filtration rate (GFR) estimating
equations using standardized creatinine (CR) and cystatin C (CYS) assays have comprised …