Definition, causes, pathogenesis, and consequences of chronic obstructive pulmonary disease exacerbations

AI Ritchie, JA Wedzicha - Clinics in chest medicine, 2020 - chestmed.theclinics.com
Acute exacerbations of chronic obstructive pulmonary disease (AECOPDs) are episodes of
symptom worsening 1 that have significant adverse consequences for patients. 2 The …

[HTML][HTML] Global and regional estimates of COPD prevalence: Systematic review and meta–analysis

D Adeloye, S Chua, C Lee, C Basquill… - Journal of global …, 2015 - ncbi.nlm.nih.gov
Background The burden of chronic obstructive pulmonary disease (COPD) across many
world regions is high. We aim to estimate COPD prevalence and number of disease cases …

[HTML][HTML] Cognitive impairments four months after COVID-19 hospital discharge: Pattern, severity and association with illness variables

KW Miskowiak, S Johnsen, SM Sattler, S Nielsen… - European …, 2021 - Elsevier
Abstract The ongoing Coronavirus Disease 2019 (COVID-19) pandemic has affected more
than 100 million people and clinics are being established for diagnosing and treating …

Pulmonary function and radiologic features in survivors of critical COVID-19: a 3-month prospective cohort

J González, ID Benítez, P Carmona, S Santisteve… - Chest, 2021 - Elsevier
Background More than 20% of hospitalized patients with COVID-19 demonstrate ARDS
requiring ICU admission. The long-term respiratory sequelae in such patients remain …

[HTML][HTML] Integrative microbiomics in bronchiectasis exacerbations

M Mac Aogain, JK Narayana, PY Tiew, NABM Ali… - Nature medicine, 2021 - nature.com
Bronchiectasis, a progressive chronic airway disease, is characterized by microbial
colonization and infection. We present an approach to the multi-biome that integrates …

Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease 2017 report. GOLD executive summary

CF Vogelmeier, GJ Criner, FJ Martinez… - American journal of …, 2017 - atsjournals.org
This Executive Summary of the Global Strategy for the Diagnosis, Management, and
Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 …

Comparison of World Health Organization and Asia-Pacific body mass index classifications in COPD patients

JU Lim, JH Lee, JS Kim, YI Hwang, TH Kim… - … journal of chronic …, 2017 - Taylor & Francis
Introduction A low body mass index (BMI) is associated with increased mortality and low
health-related quality of life in patients with COPD. The Asia-Pacific classification of BMI has …

Triple therapy with budesonide/glycopyrrolate/formoterol fumarate with co-suspension delivery technology versus dual therapies in chronic obstructive pulmonary …

GT Ferguson, KF Rabe, FJ Martinez… - The Lancet …, 2018 - thelancet.com
Background Inhaled corticosteroids have been used in patients with chronic obstructive
pulmonary disease (COPD), but the potential benefits of their use in triple therapy are not …

[HTML][HTML] Hypoxia and inflammation: insights from high-altitude physiology

K Pham, K Parikh, EC Heinrich - Frontiers in physiology, 2021 - frontiersin.org
The key regulators of the transcriptional response to hypoxia and inflammation (hypoxia
inducible factor, HIF, and nuclear factor-kappa B, NF-κB, respectively) are evolutionarily …

[HTML][HTML] Mepolizumab for eosinophilic chronic obstructive pulmonary disease

ID Pavord, P Chanez, GJ Criner… - … England Journal of …, 2017 - Mass Medical Soc
Background Patients with chronic obstructive pulmonary disease (COPD) with an
eosinophilic phenotype may benefit from treatment with mepolizumab, a monoclonal …