DJ‐1 is not a deglycase and makes a modest contribution to cellular defense against methylglyoxal damage in neurons

MC Mazza, SC Shuck, J Lin, MA Moxley… - Journal of …, 2022 - Wiley Online Library
Human DJ‐1 is a cytoprotective protein whose absence causes Parkinson's disease and is
also associated with other diseases. DJ‐1 has an established role as a redox‐regulated …

Human induced pluripotent stem cell phenotyping and preclinical Modeling of familial Parkinson's disease

J Kim, EW Daadi, T Oh, ES Daadi, MM Daadi - Genes, 2022 - mdpi.com
Parkinson's disease (PD) is primarily idiopathic and a highly heterogenous
neurodegenerative disease with patients experiencing a wide array of motor and non-motor …

DJ-1 glyoxalase activity makes a modest contribution to cellular defense against methylglyoxal damage in neurons

MC Mazza, S Shuck, J Lin, MA Moxley, J Termini… - bioRxiv, 2022 - biorxiv.org
Human DJ-1 is a cytoprotective protein whose absence causes Parkinson's disease and is
also associated with other diseases. DJ-1 has an established role as a redox-regulated …

[PDF][PDF] Advances in the Research of Common Neurodegenerative Diseases Using CRISPR-Cas9 System and hiPSCs.

S Saha - International Journal of High School …, 2024 - terra-docs.s3.us-east-2.amazonaws …
The CRISPR (Clustered Regulatory Interspaced Short Palindromic Repeats)–Cas9
(CRISPR Associated) system has become the most widely used gene editing tool due to its …

[PDF][PDF] Aplicaciones del sistema CRISPR/Cas9 en las enfermedades de Alzheimer, Parkinson y Huntington

SG FUENTES - 2022 - repositorioinstitucional.buap.mx
Según las predicciones de la OMS, para el año 2040 las enfermedades
neurodegenerativas superarán al cáncer para convertirse en la segunda causa de muerte a …

The utilization of CRISPR-Cas9 with human pluripotent stem cell for Parkinson's disease modeling

Y He, X Xing - Theoretical and Natural Science, 2024 - ewadirect.com
Parkinson's disease (PD), also often referred to as" parkinsonism," is a neurodegenerative
disorder. Those afflicted with this condition are frequently elderly, which results in a …