Neurosteroid receptor modulators for treating traumatic brain injury
TA Verdoorn, TJ Parry, G Pinna, J Lifshitz - Neurotherapeutics, 2023 - Elsevier
Traumatic brain injury (TBI) triggers wide-ranging pathology that impacts multiple
biochemical and physiological systems, both inside and outside the brain. Functional …
biochemical and physiological systems, both inside and outside the brain. Functional …
Exploring the Transmembrane Allostery in MexB: DB08385 Variant as Promising Inhibitor like Candidate Against Pseudomonas aeruginosa Antibiotic Resistance–A …
Pseudomonas aeruginosa, a formidable pathogen renowned for its antimicrobial resistance,
poses a significant threat to immunocompromised individuals. In that respect, the MexAB …
poses a significant threat to immunocompromised individuals. In that respect, the MexAB …
Improving the Solubility and Bioavailability of Progesterone Cocrystals with Selected Carboxylic Acids
J Xiong, D Xu, H Zhang, Y Shi, X Wu, S Wang - Pharmaceutics, 2024 - mdpi.com
Progesterone (PROG) is a natural steroid hormone with low solubility and high permeability
that belongs to biopharmaceutics classification system class II. In this study, novel …
that belongs to biopharmaceutics classification system class II. In this study, novel …
Amine‐Carbamate Self‐Immolative Spacers Counterintuitively Release 3° Alcohol at Much Faster Rates than 1° Alcohol Payloads
M Mason, L Bisbal Lopez, F Bashiri, A Herrero… - …, 2024 - Wiley Online Library
Self‐immolative (SI) spacers are degradable chemical connectors widely used in prodrugs
and drug conjugates to release pharmaceutical ingredients in response to specific stimuli …
and drug conjugates to release pharmaceutical ingredients in response to specific stimuli …
Microglial polarization pathways and therapeutic drugs targeting activated microglia in traumatic brain injury
L Shi, S Liu, J Chen, H Wang, Z Wang - Neural Regeneration Research - journals.lww.com
Traumatic brain injury can be categorized into primary and secondary injuries. Secondary
injuries are the main cause of disability following traumatic brain injury, which involves a …
injuries are the main cause of disability following traumatic brain injury, which involves a …
[引用][C] YOU CAN'T ALWAYS GET WHAT YOU WANT. BUT IF YOU TRY SOMETIMES, YOU GET WHAT YOU NEED: INSIGHTS FROM MY UNLIKELY CAREER IN …
D Liotta - 2023 Medicinal Chemistry Reviews, 2023 - ACS Publications