Mitigating metal-organic framework (MOF) toxicity for biomedical applications

P Wiśniewska, J Haponiuk, MR Saeb, N Rabiee… - Chemical Engineering …, 2023 - Elsevier
Metal-organic frameworks (MOFs) are a novel class of crystalline porous materials,
consisting of metal ions and organic linkers. These hybrid materials possess exceptional …

The use of RNA-based treatments in the field of cancer immunotherapy

M Chehelgerdi, M Chehelgerdi - Molecular Cancer, 2023 - Springer
Over the past several decades, mRNA vaccines have evolved from a theoretical concept to a
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …

Multifunctional self-assembled peptide hydrogels for biomedical applications

M Sedighi, N Shrestha, Z Mahmoudi, Z Khademi… - Polymers, 2023 - mdpi.com
Self-assembly is a growth mechanism in nature to apply local interactions forming a
minimum energy structure. Currently, self-assembled materials are considered for …

Factors influencing the antimicrobial mechanism of chitosan action and its derivatives: A review

M Nasaj, M Chehelgerdi, B Asghari… - International journal of …, 2024 - Elsevier
Chitosan, a versatile amino polysaccharide biopolymer derived from chitin, exhibits broad-
spectrum antimicrobial activity against various pathogenic microorganisms, including gram …

Injectable Lignin-co-Gelatin Cryogels with Antioxidant and Antibacterial Properties for Biomedical Applications

T Abdullah, T Colombani, T Alade… - …, 2021 - ACS Publications
For several biomedical applications, it is essential to develop novel bioactive materials.
Such biomaterials could potentially improve wound healing, prevent infections, or be used in …

Peptides for vaccine development

IW Hamley - ACS Applied Bio Materials, 2022 - ACS Publications
This review discusses peptide epitopes used as antigens in the development of vaccines in
clinical trials as well as future vaccine candidates. It covers peptides used in potential …

Nanovaccine-based strategies for lymph node targeted delivery and imaging in tumor immunotherapy

A He, X Li, Z Dai, Q Li, Y Zhang, M Ding, Z Wen… - Journal of …, 2023 - Springer
Therapeutic tumor vaccines have attracted considerable attention in the past decade; they
can induce tumor regression, eradicate minimal residual disease, establish lasting immune …

Self-assembled nanoplatforms for chemodynamic therapy

X Meng, Z Sun, H Chu, Y Wang - Chemical Engineering Journal, 2024 - Elsevier
Chemodynamic therapy (CDT) is an emerging tumor treatment that produces highly toxic
hydroxyl radicals (· OH) by activating the Fenton reaction in tumors to kill tumor cells. CDT is …

Peptide-containing nanoformulations: Skin barrier penetration and activity contribution

T Zhang, X Luo, K Xu, W Zhong - Advanced Drug Delivery Reviews, 2023 - Elsevier
Transdermal drug delivery presents a less invasive pathway, circumventing the need to pass
through the gastrointestinal tract and liver, thereby reducing drug breakdown, initial …

The influence of component structural arrangement on peptide vaccine immunogenicity

N Alharbi, M Skwarczynski, I Toth - Biotechnology Advances, 2022 - Elsevier
Peptide-based subunit vaccines utilise minimal immunogenic components (ie peptides) to
generate highly specific immune responses, without triggering adverse reactions. However …